Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F11%3A10081782" target="_blank" >RIV/00216208:11150/11:10081782 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00179906:_____/11:10081782

Výsledek na webu

<a href="http://www.nature.com/hr/journal/v34/n1/full/hr2010183a.html" target="_blank" >http://www.nature.com/hr/journal/v34/n1/full/hr2010183a.html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/hr.2010.183" target="_blank" >10.1038/hr.2010.183</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy

Popis výsledku v původním jazyce

Difficult-to-control arterial hypertension is a common medical problem that may result from severe hypertensive disease or from poor adherence to the recommended medical treatment. The use of serum levels of prescribed antihypertensive drugs to evaluatethe adherence in individuals with difficult-to-control arterial hypertension was descibed. Serum drug levels (SDLs) were evaluated by liquid chromatography with mass spectrometry. Eighty-four patients who presented with uncontrolled blood pressure despite the recommended combination of at least three antihypertensives were enrolled in the study. In 55 (65.5%) patients, non-adherence was diagnosed. Our data suggest that an assessment of SDLs might be helpful before an extensive evaluation is initiated for difficult-to-control hypertension.

Název v anglickém jazyce

Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy

Popis výsledku anglicky

Difficult-to-control arterial hypertension is a common medical problem that may result from severe hypertensive disease or from poor adherence to the recommended medical treatment. The use of serum levels of prescribed antihypertensive drugs to evaluatethe adherence in individuals with difficult-to-control arterial hypertension was descibed. Serum drug levels (SDLs) were evaluated by liquid chromatography with mass spectrometry. Eighty-four patients who presented with uncontrolled blood pressure despite the recommended combination of at least three antihypertensives were enrolled in the study. In 55 (65.5%) patients, non-adherence was diagnosed. Our data suggest that an assessment of SDLs might be helpful before an extensive evaluation is initiated for difficult-to-control hypertension.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

—

Projekt

—

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Hypertension Research

ISSN

0916-9636

e-ISSN

—

Svazek periodika

34

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

JP - Japonsko

Počet stran výsledku

4

Strana od-do

87-90

Kód UT WoS článku

000285919100018

EID výsledku v databázi Scopus

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