Insight and Hostility as Predictors and Correlates of Nonadherence in the European First Episode Schizophrenia Trial

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F13%3A10135333" target="_blank" >RIV/00216208:11150/13:10135333 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Insight and Hostility as Predictors and Correlates of Nonadherence in the European First Episode Schizophrenia Trial

Popis výsledku v původním jazyce

The association of hostility and insight ratings (PANSS items) with medication adherence measured by Hayward scale was investigated in 443 first episode patients diagnosed with schizophrenia, schizoaffective disorder or schizophreniform disorder. The patients took part in the EUFEST study. Prospectively, high hostility score at baseline significantly predicted nonadherence at 1st month of treatment and low insight at baseline significantly predicted nonadherence at months 1, 6 and 12. The increase of hostility and decrease in insight (over 4 points in PANSS ratings) resulted in an additive OR (95% cofidence limits) for both variables of 73, 5 at month 1, OR 276,1 at month 3 and OR 77,6 at month 6. Lack of insight and its decrease appear to have greaterand more stable predictive association with adherence than hostility. The effects of both variables on adherence do not interact.

Název v anglickém jazyce

Insight and Hostility as Predictors and Correlates of Nonadherence in the European First Episode Schizophrenia Trial

Popis výsledku anglicky

The association of hostility and insight ratings (PANSS items) with medication adherence measured by Hayward scale was investigated in 443 first episode patients diagnosed with schizophrenia, schizoaffective disorder or schizophreniform disorder. The patients took part in the EUFEST study. Prospectively, high hostility score at baseline significantly predicted nonadherence at 1st month of treatment and low insight at baseline significantly predicted nonadherence at months 1, 6 and 12. The increase of hostility and decrease in insight (over 4 points in PANSS ratings) resulted in an additive OR (95% cofidence limits) for both variables of 73, 5 at month 1, OR 276,1 at month 3 and OR 77,6 at month 6. Lack of insight and its decrease appear to have greaterand more stable predictive association with adherence than hostility. The effects of both variables on adherence do not interact.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FL - Psychiatrie, sexuologie

OECD FORD obor

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Projekt

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Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Clinical Psychopharmacology

ISSN

0271-0749

e-ISSN

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Svazek periodika

33

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

4

Strana od-do

258-261

Kód UT WoS článku

000316303700023

EID výsledku v databázi Scopus

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