Selected inflammatory and metabolic markers in psoriatic patients treated with Goeckerman therapy
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10294852" target="_blank" >RIV/00216208:11150/15:10294852 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00179906:_____/15:10294852
Výsledek na webu
<a href="http://www.hindawi.com/journals/mi/2015/979526/" target="_blank" >http://www.hindawi.com/journals/mi/2015/979526/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2015/979526" target="_blank" >10.1155/2015/979526</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Selected inflammatory and metabolic markers in psoriatic patients treated with Goeckerman therapy
Popis výsledku v původním jazyce
Psoriasis is associated with metabolic activity of adipose tissue which produces pro- and anti-inflammatory adipokines. Goeckerman therapy (GT) represents an effective treatment of psoriasis. This study evaluated variation of selected inflammatory and metabolic markers during GT and the relationships between the markers, severity of the disease (PASI score), body mass, and the basic characteristics of the therapy. The study was conducted on a group of patients (n=32) and on a control group (n=24). Before GT, we found significantly elevated levels of proinflammatory CRP (p<0.001) and leptin (p<0.05) in psoriatic patients (compared to the controls). The therapy significantly decreased the levels of CRP and adiponectin. We found positive correlations between CRP and total duration of GT (p<0.05) and CRP and the time of UV exposure (p<0.01) and negative correlations between adiponectin and the total duration of GT (p<0.05) and adiponectin and the application of CCT ointment (p<0.001). From
Název v anglickém jazyce
Selected inflammatory and metabolic markers in psoriatic patients treated with Goeckerman therapy
Popis výsledku anglicky
Psoriasis is associated with metabolic activity of adipose tissue which produces pro- and anti-inflammatory adipokines. Goeckerman therapy (GT) represents an effective treatment of psoriasis. This study evaluated variation of selected inflammatory and metabolic markers during GT and the relationships between the markers, severity of the disease (PASI score), body mass, and the basic characteristics of the therapy. The study was conducted on a group of patients (n=32) and on a control group (n=24). Before GT, we found significantly elevated levels of proinflammatory CRP (p<0.001) and leptin (p<0.05) in psoriatic patients (compared to the controls). The therapy significantly decreased the levels of CRP and adiponectin. We found positive correlations between CRP and total duration of GT (p<0.05) and CRP and the time of UV exposure (p<0.01) and negative correlations between adiponectin and the total duration of GT (p<0.05) and adiponectin and the application of CCT ointment (p<0.001). From
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FN - Epidemiologie, infekční nemoci a klinická imunologie
OECD FORD obor
—
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Mediators of Inflammation
ISSN
0962-9351
e-ISSN
—
Svazek periodika
2015
Číslo periodika v rámci svazku
May
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
8
Strana od-do
—
Kód UT WoS článku
000356694200001
EID výsledku v databázi Scopus
2-s2.0-84934893715