Collagen matrix as a tool in studying fibroblastic cell behavior

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10306855" target="_blank" >RIV/00216208:11150/15:10306855 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1080/19336918.2015.1005469" target="_blank" >http://dx.doi.org/10.1080/19336918.2015.1005469</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/19336918.2015.1005469" target="_blank" >10.1080/19336918.2015.1005469</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Collagen matrix as a tool in studying fibroblastic cell behavior

Popis výsledku v původním jazyce

Type I collagen is a fibrillar protein, a member of a large family of collagen proteins. It is present in most body tissues, usually in combination with other collagens and other components of extracellular matrix. Its synthesis is increased in various pathological situations, in healing wounds, in fibrotic tissues and in many tumors. After extraction from collagen-rich tissues it is widely used in studies of cell behavior, especially those of fibroblasts and myofibroblasts. Cells cultured in a classical way, on planar plastic dishes, lack the third dimension that is characteristic of body tissues. Collagen I forms gel at neutral pH and may become a basis of a 3D matrix that better mimics conditions in tissue than plastic dishes.

Název v anglickém jazyce

Collagen matrix as a tool in studying fibroblastic cell behavior

Popis výsledku anglicky

Type I collagen is a fibrillar protein, a member of a large family of collagen proteins. It is present in most body tissues, usually in combination with other collagens and other components of extracellular matrix. Its synthesis is increased in various pathological situations, in healing wounds, in fibrotic tissues and in many tumors. After extraction from collagen-rich tissues it is widely used in studies of cell behavior, especially those of fibroblasts and myofibroblasts. Cells cultured in a classical way, on planar plastic dishes, lack the third dimension that is characteristic of body tissues. Collagen I forms gel at neutral pH and may become a basis of a 3D matrix that better mimics conditions in tissue than plastic dishes.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cell Adhesion and Migration

ISSN

1933-6918

e-ISSN

—

Svazek periodika

9

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

308-316

Kód UT WoS článku

000360112100008

EID výsledku v databázi Scopus

2-s2.0-84954199370