Cervical Microbiota in Women with Preterm Prelabor Rupture of Membranes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10312443" target="_blank" >RIV/00216208:11150/15:10312443 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00179906:_____/15:10312443

Výsledek na webu

<a href="http://dx.doi.org/10.1371/journal.pone.0126884" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0126884</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1371/journal.pone.0126884" target="_blank" >10.1371/journal.pone.0126884</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cervical Microbiota in Women with Preterm Prelabor Rupture of Membranes

Popis výsledku v původním jazyce

Objective To analyze the cervical microbiota in women with preterm prelabor rupture of membranes (PPROM) by pyrosequencing and to document associations between cervical microbiota, cervical inflammatory response, microbial invasion of the amniotic cavity(MIAC), histological chorioamnionitis, and intraamniotic infection (IAI). Study Design Sixty-one women with singleton pregnancies complicated by PPROM were included in the study. Specimens of cervical and amniotic fluid were collected on admission. Thecervical microbiota was assessed by 16S rRNA gene sequencing by pyrosequencing. Interleukin (IL)-6 concentration in the cervical fluid and amniotic fluid was measured by ELISA and lateral flow immunoassay, respectively. Results Four bacterial community state types [CST I (Lactobacillus crispatus dominated), CST III (Lactobacillus iners dominated), CST IV-A (non-Lactobacillus bacteria dominated), and CST IV-B (Gardnerella vaginalis and Sneathia sanguinegens dominated)] were observed in th

Název v anglickém jazyce

Cervical Microbiota in Women with Preterm Prelabor Rupture of Membranes

Popis výsledku anglicky

Objective To analyze the cervical microbiota in women with preterm prelabor rupture of membranes (PPROM) by pyrosequencing and to document associations between cervical microbiota, cervical inflammatory response, microbial invasion of the amniotic cavity(MIAC), histological chorioamnionitis, and intraamniotic infection (IAI). Study Design Sixty-one women with singleton pregnancies complicated by PPROM were included in the study. Specimens of cervical and amniotic fluid were collected on admission. Thecervical microbiota was assessed by 16S rRNA gene sequencing by pyrosequencing. Interleukin (IL)-6 concentration in the cervical fluid and amniotic fluid was measured by ELISA and lateral flow immunoassay, respectively. Results Four bacterial community state types [CST I (Lactobacillus crispatus dominated), CST III (Lactobacillus iners dominated), CST IV-A (non-Lactobacillus bacteria dominated), and CST IV-B (Gardnerella vaginalis and Sneathia sanguinegens dominated)] were observed in th

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FK - Gynekologie a porodnictví

OECD FORD obor

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Projekt

<a href="/cs/project/NT13461" target="_blank" >NT13461: Vztah mezi množstvím bakterií v plodové vodě a intenzitou intraamniální zánětlivé odpovědi u pacientek s předčasným odtokem plodové vody</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

PLoS ONE

ISSN

1932-6203

e-ISSN

—

Svazek periodika

10

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

17

Strana od-do

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Kód UT WoS článku

000354921400082

EID výsledku v databázi Scopus

2-s2.0-84930663870