New biomarkers in the selection of patients for talcage of pleural cavity in the palliative therapy of malign pleural exudate

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10316301" target="_blank" >RIV/00216208:11150/15:10316301 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00179906:_____/15:10316301

Výsledek na webu

<a href="http://dx.doi.org/10.5507/bp.2015.005" target="_blank" >http://dx.doi.org/10.5507/bp.2015.005</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2015.005" target="_blank" >10.5507/bp.2015.005</a>

Jazyk výsledku

angličtina

Název v původním jazyce

New biomarkers in the selection of patients for talcage of pleural cavity in the palliative therapy of malign pleural exudate

Popis výsledku v původním jazyce

Background. Chemical pleurodesis using videothoracoscopically applied powdered talc under is the most effective method of palliative therapy for malign pleural exudate. Talc produces an intense systemic inflammatory reaction with the development of aseptic pleurisy. The result is obliteration of the pleural cavity. In routine practice, the course of local inflammatory markers is difficult to evaluate. Selection of suitable patients who will respond to this procedure is another principal obstacle of thissurgical method. Aim. To evaluate the course of local inflammatory changes in the pleural cavity following application of talc and to quantify their dynamics. Selection of specific biomarkers to predict the intensity of inflammation in the pleural exudate for targeted selection of patients suitable for talcage was the second aim of this study. Materials and Methods. 114 patients were retrospectively divided into Group A (N1 = 98) or patients without relace and Group B (N2 = 16), patient

Název v anglickém jazyce

New biomarkers in the selection of patients for talcage of pleural cavity in the palliative therapy of malign pleural exudate

Popis výsledku anglicky

Background. Chemical pleurodesis using videothoracoscopically applied powdered talc under is the most effective method of palliative therapy for malign pleural exudate. Talc produces an intense systemic inflammatory reaction with the development of aseptic pleurisy. The result is obliteration of the pleural cavity. In routine practice, the course of local inflammatory markers is difficult to evaluate. Selection of suitable patients who will respond to this procedure is another principal obstacle of thissurgical method. Aim. To evaluate the course of local inflammatory changes in the pleural cavity following application of talc and to quantify their dynamics. Selection of specific biomarkers to predict the intensity of inflammation in the pleural exudate for targeted selection of patients suitable for talcage was the second aim of this study. Materials and Methods. 114 patients were retrospectively divided into Group A (N1 = 98) or patients without relace and Group B (N2 = 16), patient

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical Papers

ISSN

1213-8118

e-ISSN

—

Svazek periodika

159

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

576-581

Kód UT WoS článku

000366566700010

EID výsledku v databázi Scopus

2-s2.0-84949640208