Univariate and multivariate models for the prediction of life-threatening complications in 586 cases of deep neck space infections: retrospective multi-institutional study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F17%3A10369527" target="_blank" >RIV/00216208:11150/17:10369527 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00179906:_____/17:10369527 RIV/00843989:_____/17:E0106500

Výsledek na webu

<a href="http://dx.doi.org/10.1017/S0022215117001153" target="_blank" >http://dx.doi.org/10.1017/S0022215117001153</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1017/S0022215117001153" target="_blank" >10.1017/S0022215117001153</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Univariate and multivariate models for the prediction of life-threatening complications in 586 cases of deep neck space infections: retrospective multi-institutional study

Popis výsledku v původním jazyce

Objective: To identify deep neck infection factors related to life-threatening complications. Methods: This retrospective multi-institutional study comprised 586 patients treated for deep neck infections between 2002 and 2012. The statistical significance of variables associated with life-threatening complications of deep neck infections was assessed. Results: During treatment, life-threatening complications occurred in 60 out of 586 cases. On univariate analysis, life-threatening complications were linked to: dyspnoea, neck movement disturbance and dysphonia (all p &lt; 0.001); and parapharyngeal, anterior visceral or pretracheal deep neck involvement (all p &lt; 0.002). Aetiology was significantly linked to tonsils (p &lt; 0.001). Regarding infection type, fasciitis was a significant factor (p &lt; 0.001). Candida albicans was a significant bacterial culture (p &lt; 0.001). A multivariate step-wise model disclosed fewer significant variables: retropharyngeal space (p = 0.005) and major blood vessels area (p = 0.006) involvement, and bacterial culture C albicans (p &lt; 0.001). Conclusion: It can be predicted that patients with deep neck infections, with neck movement disturbances, dysphonia, dyspnoea and swelling of the external neck, accompanied by severe pain, and inflammatory changes in the retropharyngeal space and large vessel areas, with culture-confirmed infection of C albicans, are likely to develop life-threatening complications.

Název v anglickém jazyce

Univariate and multivariate models for the prediction of life-threatening complications in 586 cases of deep neck space infections: retrospective multi-institutional study

Popis výsledku anglicky

Objective: To identify deep neck infection factors related to life-threatening complications. Methods: This retrospective multi-institutional study comprised 586 patients treated for deep neck infections between 2002 and 2012. The statistical significance of variables associated with life-threatening complications of deep neck infections was assessed. Results: During treatment, life-threatening complications occurred in 60 out of 586 cases. On univariate analysis, life-threatening complications were linked to: dyspnoea, neck movement disturbance and dysphonia (all p &lt; 0.001); and parapharyngeal, anterior visceral or pretracheal deep neck involvement (all p &lt; 0.002). Aetiology was significantly linked to tonsils (p &lt; 0.001). Regarding infection type, fasciitis was a significant factor (p &lt; 0.001). Candida albicans was a significant bacterial culture (p &lt; 0.001). A multivariate step-wise model disclosed fewer significant variables: retropharyngeal space (p = 0.005) and major blood vessels area (p = 0.006) involvement, and bacterial culture C albicans (p &lt; 0.001). Conclusion: It can be predicted that patients with deep neck infections, with neck movement disturbances, dysphonia, dyspnoea and swelling of the external neck, accompanied by severe pain, and inflammatory changes in the retropharyngeal space and large vessel areas, with culture-confirmed infection of C albicans, are likely to develop life-threatening complications.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30206 - Otorhinolaryngology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Laryngology &amp; Otology

ISSN

0022-2151

e-ISSN

—

Svazek periodika

131

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

779-784

Kód UT WoS článku

000408463400010

EID výsledku v databázi Scopus

2-s2.0-85020226198