Antibiotic Resistance in Nosocomial Bacteria Isolated from Infected Wounds of Hospitalized Patients in Czech Republic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F20%3A10417377" target="_blank" >RIV/00216208:11150/20:10417377 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00179906:_____/20:10417377 RIV/00064190:_____/20:N0000061 RIV/60162694:G44__/20:00555865 RIV/61989592:15110/20:73605662

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=03KY.Xu8ua" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=03KY.Xu8ua</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/antibiotics9060342" target="_blank" >10.3390/antibiotics9060342</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Antibiotic Resistance in Nosocomial Bacteria Isolated from Infected Wounds of Hospitalized Patients in Czech Republic

Popis výsledku v původním jazyce

Hospitalized patients with wounds face an increased risk of infection with multi-drug-resistant nosocomial bacteria. In this study, samples from almost 10,000 patients from big hospitals in Czech Republic with infected wounds were analyzed for the presence of bacterial pathogens. In 7693 patients (78.8%), bacterial etiological agents were identified. Members of theEnterobacterales(37.1%) andStaphyloccus aureus(21.1%) were the most prevalent pathogens.Staphyloccus aureusshowed methicillin resistance in 8.6%. Almost half of theKlebsiella pneumoniaeisolates were ESBL-positive and 25.6% of theEnterobacterspp. isolates were AmpC-positive. The third most prevalentPseudomonas aeruginosashowed resistance to 19-32% of the antipseudomonal antibiotics tested. Based on the results, amoxicillin/clavulanic acid, ampicillin/sulbactam or piperacillin/tazobactam combined with gentamicin can be recommended for antibiotic treatment of infected wounds. Once the etiological agent is identified, the therapy should be adjusted according to the species and its resistance.

Název v anglickém jazyce

Antibiotic Resistance in Nosocomial Bacteria Isolated from Infected Wounds of Hospitalized Patients in Czech Republic

Popis výsledku anglicky

Hospitalized patients with wounds face an increased risk of infection with multi-drug-resistant nosocomial bacteria. In this study, samples from almost 10,000 patients from big hospitals in Czech Republic with infected wounds were analyzed for the presence of bacterial pathogens. In 7693 patients (78.8%), bacterial etiological agents were identified. Members of theEnterobacterales(37.1%) andStaphyloccus aureus(21.1%) were the most prevalent pathogens.Staphyloccus aureusshowed methicillin resistance in 8.6%. Almost half of theKlebsiella pneumoniaeisolates were ESBL-positive and 25.6% of theEnterobacterspp. isolates were AmpC-positive. The third most prevalentPseudomonas aeruginosashowed resistance to 19-32% of the antipseudomonal antibiotics tested. Based on the results, amoxicillin/clavulanic acid, ampicillin/sulbactam or piperacillin/tazobactam combined with gentamicin can be recommended for antibiotic treatment of infected wounds. Once the etiological agent is identified, the therapy should be adjusted according to the species and its resistance.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30303 - Infectious Diseases

Projekt

<a href="/cs/project/NV17-31765A" target="_blank" >NV17-31765A: Potenciál xanthohumolu a beta hořkých kyselin pro léčbu nozokomiálních infekcí</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Antibiotics [online]

ISSN

2079-6382

e-ISSN

—

Svazek periodika

9

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

8

Strana od-do

342

Kód UT WoS článku

000551242300001

EID výsledku v databázi Scopus

2-s2.0-85086663711