The Amaryllidaceae alkaloids haemanthamine, haemanthidine and their semisynthetic derivatives as potential drugs

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F21%3A10425668" target="_blank" >RIV/00216208:11150/21:10425668 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11160/21:10425668

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Qat3MsKPZd" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Qat3MsKPZd</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11101-020-09675-8" target="_blank" >10.1007/s11101-020-09675-8</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The Amaryllidaceae alkaloids haemanthamine, haemanthidine and their semisynthetic derivatives as potential drugs

Popis výsledku v původním jazyce

Plants of the Amaryllidaceae family, have a wide distribution through both tropical and sub-tropical regions of the world. They have also a long and notable place in the history of traditional and Western medicine. Amaryllidaceae alkaloids are a structurally diverse group of plant metabolites with a wide range of biological properties including antimalarial, antitumor, antimicrobial, antiviral, enzyme inhibitory, antioxidant, anticonvulsant and antifungal activities. Among them, the haemanthamine-type alkaloids, which have the 5,10b-ethanophenanthridine skeleton as the core structure, represented by haemanthamine and haemanthidine, have received considerable attention, since they have been reported to possess antitumor properties. The present review aims to summarize comprehensively the research that has been published on the Amaryllidaceae alkaloids haemanthamine and haemanthidine.

Název v anglickém jazyce

The Amaryllidaceae alkaloids haemanthamine, haemanthidine and their semisynthetic derivatives as potential drugs

Popis výsledku anglicky

Plants of the Amaryllidaceae family, have a wide distribution through both tropical and sub-tropical regions of the world. They have also a long and notable place in the history of traditional and Western medicine. Amaryllidaceae alkaloids are a structurally diverse group of plant metabolites with a wide range of biological properties including antimalarial, antitumor, antimicrobial, antiviral, enzyme inhibitory, antioxidant, anticonvulsant and antifungal activities. Among them, the haemanthamine-type alkaloids, which have the 5,10b-ethanophenanthridine skeleton as the core structure, represented by haemanthamine and haemanthidine, have received considerable attention, since they have been reported to possess antitumor properties. The present review aims to summarize comprehensively the research that has been published on the Amaryllidaceae alkaloids haemanthamine and haemanthidine.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

<a href="/cs/project/EF18_069%2F0010046" target="_blank" >EF18_069/0010046: Předaplikační výzkum inovativních léčiv a medicínských technologií</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Phytochemistry Reviews

ISSN

1568-7767

e-ISSN

—

Svazek periodika

20

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

21

Strana od-do

303-323

Kód UT WoS článku

000530961400001

EID výsledku v databázi Scopus

2-s2.0-85085144661