European Validation of the Self-evaluation of Negative Symptoms (SNS): A Large Multinational and Multicenter Study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F22%3A10436902" target="_blank" >RIV/00216208:11150/22:10436902 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00179906:_____/22:10436902

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=c3XlbrN4F0" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=c3XlbrN4F0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fpsyt.2022.826465" target="_blank" >10.3389/fpsyt.2022.826465</a>

Jazyk výsledku

angličtina

Název v původním jazyce

European Validation of the Self-evaluation of Negative Symptoms (SNS): A Large Multinational and Multicenter Study

Popis výsledku v původním jazyce

Negative symptoms are usually evaluated with scales based on observer ratings and up to now self-assessments have been overlooked. The aim of this paper was to validate the Self-evaluation of Negative Symptoms (SNS) in a large European sample coming from 12 countries. We wanted to demonstrate: 1- good convergent and divergent validities; 2- relationships between SNS scores and patients&apos; functional outcome; 3- the capacity of the SNS compared to the Brief Negative Symptom Scale (BNSS) to detect negative symptoms; 4- a five-domain construct in relation to the 5 consensus domains (social withdrawal, anhedonia, alogia, avolition, blunted affect) as the best latent structure of SNS. Methods: Two hundred forty-five subjects with a DSM-IV diagnosis of schizophrenia completed the SNS, the Positive and Negative Syndrome Scale (PANSS), the BNSS, the Calgary Depression Scale for Schizophrenia (CDSS), and the Personal and Social Performance (PSP) scale. Results: Significant positive correlations were observed between the total score of the SNS and the total scores of the PANSS negative subscale (r= 0.37; P &lt; 0.0001) and the BNSS (r= 0.43; p &lt;0.0001). SNS scores did not correlate with the level of insight, parkinsonism, or the total score of the PANSS positive subscale. A positive correlation was found between SNS and CDSS (r = 0.35; p &lt; 0.0001). Among the 5 SNS subscores, only avolition subscores entered the regression equation explaining a lower functional outcome. The 1-factor and 2-factor models provided poor fit, while the 5- factor model and the hierarchical model provided the best fit, with a small advantage of the 5-factor model. The frequency of each negative dimension was systematically higher using the BNSS and the SNS versus the PANSS and was higher for alogia and avolition using SNS versus BNSS. Conclusion: In a large European multicentric sample, this study demonstrated that the SNS has: 1-good psychometric properties with good convergent and divergent validities; 2- a five-factor latent structure; 3- a large association with patients&apos; functional outcome; and 4- the capacity to identify subjects with negative symptoms that is close to the BNSS and superior to the PANSS negative subscale.

Název v anglickém jazyce

European Validation of the Self-evaluation of Negative Symptoms (SNS): A Large Multinational and Multicenter Study

Popis výsledku anglicky

Negative symptoms are usually evaluated with scales based on observer ratings and up to now self-assessments have been overlooked. The aim of this paper was to validate the Self-evaluation of Negative Symptoms (SNS) in a large European sample coming from 12 countries. We wanted to demonstrate: 1- good convergent and divergent validities; 2- relationships between SNS scores and patients&apos; functional outcome; 3- the capacity of the SNS compared to the Brief Negative Symptom Scale (BNSS) to detect negative symptoms; 4- a five-domain construct in relation to the 5 consensus domains (social withdrawal, anhedonia, alogia, avolition, blunted affect) as the best latent structure of SNS. Methods: Two hundred forty-five subjects with a DSM-IV diagnosis of schizophrenia completed the SNS, the Positive and Negative Syndrome Scale (PANSS), the BNSS, the Calgary Depression Scale for Schizophrenia (CDSS), and the Personal and Social Performance (PSP) scale. Results: Significant positive correlations were observed between the total score of the SNS and the total scores of the PANSS negative subscale (r= 0.37; P &lt; 0.0001) and the BNSS (r= 0.43; p &lt;0.0001). SNS scores did not correlate with the level of insight, parkinsonism, or the total score of the PANSS positive subscale. A positive correlation was found between SNS and CDSS (r = 0.35; p &lt; 0.0001). Among the 5 SNS subscores, only avolition subscores entered the regression equation explaining a lower functional outcome. The 1-factor and 2-factor models provided poor fit, while the 5- factor model and the hierarchical model provided the best fit, with a small advantage of the 5-factor model. The frequency of each negative dimension was systematically higher using the BNSS and the SNS versus the PANSS and was higher for alogia and avolition using SNS versus BNSS. Conclusion: In a large European multicentric sample, this study demonstrated that the SNS has: 1-good psychometric properties with good convergent and divergent validities; 2- a five-factor latent structure; 3- a large association with patients&apos; functional outcome; and 4- the capacity to identify subjects with negative symptoms that is close to the BNSS and superior to the PANSS negative subscale.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30215 - Psychiatry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Frontiers in Psychiatry

ISSN

1664-0640

e-ISSN

1664-0640

Svazek periodika

13

Číslo periodika v rámci svazku

JAN

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

13

Strana od-do

826465

Kód UT WoS článku

000756944900001

EID výsledku v databázi Scopus

2-s2.0-85124580911