Effect of Dioptric Blur on Pattern-Reversal and Motion-Onset VEPs as Used in Clinical Research

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F22%3A10453920" target="_blank" >RIV/00216208:11150/22:10453920 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=5crI7W9N.0" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=5crI7W9N.0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1167/tvst.11.12.7" target="_blank" >10.1167/tvst.11.12.7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effect of Dioptric Blur on Pattern-Reversal and Motion-Onset VEPs as Used in Clinical Research

Popis výsledku v původním jazyce

Purpose: To describe the effect of dioptric blur on visual evoked potentials (VEPs) induced by motion onset (MO-VEPs).Methods: The effect of dioptric blur up to 4 D on MO-VEPs was tested on 12 subjects using central, peripheral, and full-field stimulation with a low-contrast structure of concentric circles with spatial frequency &lt;1 c/°. The results were compared to VEPs evoked by 15ʹ and 60ʹ checkerboard pattern-reversal (PR-VEPs). The relationship between peak time and interpeak amplitude of the dominant components was related to the level of dioptric blur using linear regression.Results: The MO-VEPs did not show a significant peak prolongation (P &gt; 0.28) or amplitude attenuation (P &gt; 0.14) with the blur, whereas for the PR-VEPs we observed a significant decrease in amplitude (P &lt; 0.001) and increase in peak time (P &lt; 0.001) for both checkerboard sizes.Conclusions: For MO-VEPs induced by radial motion of low contrast and low spatial frequency pattern, the change in retinal blur does not affect the peak time or the interpeak amplitude of the dominant N2 component.Translational Relevance: The resistance to retinal blur that we demonstrated for MO-VEP provides a diagnostic opportunity to test the integrity of the visual system and reveal a retrobulbar impairment even in uncorrected refractive errors.

Název v anglickém jazyce

Effect of Dioptric Blur on Pattern-Reversal and Motion-Onset VEPs as Used in Clinical Research

Popis výsledku anglicky

Purpose: To describe the effect of dioptric blur on visual evoked potentials (VEPs) induced by motion onset (MO-VEPs).Methods: The effect of dioptric blur up to 4 D on MO-VEPs was tested on 12 subjects using central, peripheral, and full-field stimulation with a low-contrast structure of concentric circles with spatial frequency &lt;1 c/°. The results were compared to VEPs evoked by 15ʹ and 60ʹ checkerboard pattern-reversal (PR-VEPs). The relationship between peak time and interpeak amplitude of the dominant components was related to the level of dioptric blur using linear regression.Results: The MO-VEPs did not show a significant peak prolongation (P &gt; 0.28) or amplitude attenuation (P &gt; 0.14) with the blur, whereas for the PR-VEPs we observed a significant decrease in amplitude (P &lt; 0.001) and increase in peak time (P &lt; 0.001) for both checkerboard sizes.Conclusions: For MO-VEPs induced by radial motion of low contrast and low spatial frequency pattern, the change in retinal blur does not affect the peak time or the interpeak amplitude of the dominant N2 component.Translational Relevance: The resistance to retinal blur that we demonstrated for MO-VEP provides a diagnostic opportunity to test the integrity of the visual system and reveal a retrobulbar impairment even in uncorrected refractive errors.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30207 - Ophthalmology

Projekt

<a href="/cs/project/NV18-06-00484" target="_blank" >NV18-06-00484: Zlepšení kvality života u pacientů se stabilní makulopatií prostřednictvím implantace intraokulární makulární čočky a modulací zrakové plasticity transkraniální elektrickou stimulací</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Translational Vision Science &amp; Technology

ISSN

2164-2591

e-ISSN

—

Svazek periodika

11

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

7

Kód UT WoS článku

000956649200001

EID výsledku v databázi Scopus

2-s2.0-85143545889