Prognostic value of respiratory quotients in severe polytrauma patients with nutritional support

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F18%3A10376076" target="_blank" >RIV/00216208:11160/18:10376076 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00179906:_____/18:10376076

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0899900717302393" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0899900717302393</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.nut.2017.10.013" target="_blank" >10.1016/j.nut.2017.10.013</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Prognostic value of respiratory quotients in severe polytrauma patients with nutritional support

Popis výsledku v původním jazyce

Objective: The association between energy metabolism and prognosis in polytrauma patients has not yet been defined. The aim of this study was to describe energy metabolism and analyze the prognostic value of respiratory quotient (RQ) and nonprotein respiratory quotient (npRQ) in fasting polytrauma patients (fPP) and polytrauma patients with nutritional support (nsPP). Methods: Twenty-two polytrauma patients (before and after parenteral nutrition administration) and 22 healthy controls (after overnight fasting) were examined on day 4 (median) after admission to the intensive care unit. To evaluate energy expenditure in nsPP and resting energy expenditure in fPP and controls with RQ and npRQ in all groups, we used indirect calorimetry. With regression analysis, the descriptive models of intensive care unit (ICU) length of stay (LOS) and mechanical ventilation time (VT) were derived. Results: RQ and npRQ were significantly lower in fPP than in controls (P &lt; 0.05 and P &lt; 0.01, respectively) and in nsPP (P &lt; 0.05). In nsPP, relationships between RQ or npRQ and the ICU LOS or mechanical VT were demonstrated (P &lt; 0.0001, r = -0.78 for RQ and VT; P &lt; 0.0001, r = -0.78 for npRQ and VT; P &lt; 0.001, r = -0.69 for RQ and LOS; P &lt; 0.001, r = -0.72 for npRQ and LOS). Conclusions: RQ and npRQ parameters measured by indirect calorimetry in polytrauma patients with par enteral nutrition on the fourth day of ICU stay related to clinical outcomes such as duration of mechanical ventilation and ICU LOS.

Název v anglickém jazyce

Prognostic value of respiratory quotients in severe polytrauma patients with nutritional support

Popis výsledku anglicky

Objective: The association between energy metabolism and prognosis in polytrauma patients has not yet been defined. The aim of this study was to describe energy metabolism and analyze the prognostic value of respiratory quotient (RQ) and nonprotein respiratory quotient (npRQ) in fasting polytrauma patients (fPP) and polytrauma patients with nutritional support (nsPP). Methods: Twenty-two polytrauma patients (before and after parenteral nutrition administration) and 22 healthy controls (after overnight fasting) were examined on day 4 (median) after admission to the intensive care unit. To evaluate energy expenditure in nsPP and resting energy expenditure in fPP and controls with RQ and npRQ in all groups, we used indirect calorimetry. With regression analysis, the descriptive models of intensive care unit (ICU) length of stay (LOS) and mechanical ventilation time (VT) were derived. Results: RQ and npRQ were significantly lower in fPP than in controls (P &lt; 0.05 and P &lt; 0.01, respectively) and in nsPP (P &lt; 0.05). In nsPP, relationships between RQ or npRQ and the ICU LOS or mechanical VT were demonstrated (P &lt; 0.0001, r = -0.78 for RQ and VT; P &lt; 0.0001, r = -0.78 for npRQ and VT; P &lt; 0.001, r = -0.69 for RQ and LOS; P &lt; 0.001, r = -0.72 for npRQ and LOS). Conclusions: RQ and npRQ parameters measured by indirect calorimetry in polytrauma patients with par enteral nutrition on the fourth day of ICU stay related to clinical outcomes such as duration of mechanical ventilation and ICU LOS.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Nutrition

ISSN

0899-9007

e-ISSN

—

Svazek periodika

49

Číslo periodika v rámci svazku

May

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

90-95

Kód UT WoS článku

000429500700014

EID výsledku v databázi Scopus

2-s2.0-85042629755