Concentration dependent SERS study of a bioactive methylsulfonyl derivative

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F22%3A10450999" target="_blank" >RIV/00216208:11160/22:10450999 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8V07DnM39v" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8V07DnM39v</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.molliq.2022.120557" target="_blank" >10.1016/j.molliq.2022.120557</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Concentration dependent SERS study of a bioactive methylsulfonyl derivative

Popis výsledku v původním jazyce

Concentration dependent surface enhanced Raman scattering (SERS) studies of biologically active methylsulfonyl derivative (BMSP) are reported. Out of various concentrations, SERS at 10(-3) M gives maximum enhancement. The experimental results are supported by theoretical investigations. BMSP exhibited selective micro molar activity against Staphylococcus aureus. The interaction of charge transfer between Ag and S atoms is confirmed by the enhanced bond length values. Reduction in ionization potential suggests that the BMSP-Ag6 system has stronger electron donating characteristics than BMSP. The electrophilicity index of the adsorbed system containing BMSP and silver cluster represent biological activity and the adsorption process is chemisorption. Presence of CH3 modes in the SERS spectrum suggest that the molecule adopts a tilted orientation, and that para-substituted phenyl ring is more slanted than poly-substituted phenyl ring. Presence of ring stretches, bending modes for all concentrations suggest that the BMSP molecule may tilt, resulting in an interaction with the metal surface and there is an orientation change for the molecule with respect to the metal surface as concentration changes.

Název v anglickém jazyce

Concentration dependent SERS study of a bioactive methylsulfonyl derivative

Popis výsledku anglicky

Concentration dependent surface enhanced Raman scattering (SERS) studies of biologically active methylsulfonyl derivative (BMSP) are reported. Out of various concentrations, SERS at 10(-3) M gives maximum enhancement. The experimental results are supported by theoretical investigations. BMSP exhibited selective micro molar activity against Staphylococcus aureus. The interaction of charge transfer between Ag and S atoms is confirmed by the enhanced bond length values. Reduction in ionization potential suggests that the BMSP-Ag6 system has stronger electron donating characteristics than BMSP. The electrophilicity index of the adsorbed system containing BMSP and silver cluster represent biological activity and the adsorption process is chemisorption. Presence of CH3 modes in the SERS spectrum suggest that the molecule adopts a tilted orientation, and that para-substituted phenyl ring is more slanted than poly-substituted phenyl ring. Presence of ring stretches, bending modes for all concentrations suggest that the BMSP molecule may tilt, resulting in an interaction with the metal surface and there is an orientation change for the molecule with respect to the metal surface as concentration changes.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Molecular Liquids

ISSN

0167-7322

e-ISSN

1873-3166

Svazek periodika

367

Číslo periodika v rámci svazku

December

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

120557

Kód UT WoS článku

000880312600012

EID výsledku v databázi Scopus

2-s2.0-85139992423