Translational animal models for sexual health

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11240%2F23%3A10478066" target="_blank" >RIV/00216208:11240/23:10478066 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.uv.mx/personal/jmanzo/files/2023/09/Libro-Translacional.pdf" target="_blank" >https://www.uv.mx/personal/jmanzo/files/2023/09/Libro-Translacional.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Translational animal models for sexual health

Popis výsledku v původním jazyce

The advent of sildenafil heral died in a &quot;third se sexual revolution&quot; of information about the physiology of sexual behavior. But even prior to this, sophisticated behavioral paradigms were being developed to optimize the recording of sexual responses in rodents and other species and the ability to observe more appetitive aspects of sexual interaction in both females and males (Erskine, 1985; McClintock, 1984; Mendel son and Gorzalka, 1987; Pfaus et al., 1990; Pfaus et al., 1999). The use of the CPP paradigm showed that both male and female rats found particular types of sexual stimulation rewarding (Agmo and Berenfeld, 1990; Martínez and Paredes, 2001; Paredes and Alonso, 1997; Paredes and Vazquez, 1999). The addition of partner preference paradigms helped to reveal the neurochemical substrates of sexual reward and how they are related to the stimulation of sexual desire and arousal. Thus, the innovative use of these behavioral paradigms offers researchers the opportunity to collect preclinical data that have a high degree of predictive validity to human sexual responses and that translate - literally - from the bench to the bedside.

Název v anglickém jazyce

Translational animal models for sexual health

Popis výsledku anglicky

The advent of sildenafil heral died in a &quot;third se sexual revolution&quot; of information about the physiology of sexual behavior. But even prior to this, sophisticated behavioral paradigms were being developed to optimize the recording of sexual responses in rodents and other species and the ability to observe more appetitive aspects of sexual interaction in both females and males (Erskine, 1985; McClintock, 1984; Mendel son and Gorzalka, 1987; Pfaus et al., 1990; Pfaus et al., 1999). The use of the CPP paradigm showed that both male and female rats found particular types of sexual stimulation rewarding (Agmo and Berenfeld, 1990; Martínez and Paredes, 2001; Paredes and Alonso, 1997; Paredes and Vazquez, 1999). The addition of partner preference paradigms helped to reveal the neurochemical substrates of sexual reward and how they are related to the stimulation of sexual desire and arousal. Thus, the innovative use of these behavioral paradigms offers researchers the opportunity to collect preclinical data that have a high degree of predictive validity to human sexual responses and that translate - literally - from the bench to the bedside.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

50101 - Psychology (including human - machine relations)

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

From Animal Models to Humans: translational research toward human health

ISBN

978-607-595-604-6

Počet stran výsledku

45

Strana od-do

151-195

Počet stran knihy

337

Název nakladatele

Universidad Veracruzana

Místo vydání

Xalapa

Kód UT WoS kapitoly

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