Singlet Oxygen Imaging in Polymeric Nanofibers by Delayed Fluorescence
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F10%3A10061886" target="_blank" >RIV/00216208:11310/10:10061886 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61388980:_____/10:00351766 RIV/61388955:_____/10:00351766
Výsledek na webu
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DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Singlet Oxygen Imaging in Polymeric Nanofibers by Delayed Fluorescence
Popis výsledku v původním jazyce
Polymeric nanofiber materials loaded with photosensitizers exhibit significant antibacterial activity due to their generation of cytotoxic singlet oxygen O2(1deltag). A time-gated fluorescence imaging technique was used to monitor the photosensitized processes in polystyrene (PS) and gelatin (GE) nanofibers loaded with 0.1 wt % tetraphenylporphyrin (TPP) photosensitizer. The fluorescence decay of TPP at the periphery of the PS nanofibers was single exponential. Increased fluorescence quenching was observed in the domains with higher TPP loading, located in the center of the nanofibers, and added a shorter lifetime component to the kinetics. The domains exhibiting singlet oxygen activity within the nanofibers were visualized and analyzed by singlet oxygen-sensitized delayed fluorescence imaging (SODF). Whereas O2(1deltag) was produced in PS nanofibers, its production in GE nanofibers was limited. These results were confirmed by time-resolved phosphorescence measurements at 1270 nm.
Název v anglickém jazyce
Singlet Oxygen Imaging in Polymeric Nanofibers by Delayed Fluorescence
Popis výsledku anglicky
Polymeric nanofiber materials loaded with photosensitizers exhibit significant antibacterial activity due to their generation of cytotoxic singlet oxygen O2(1deltag). A time-gated fluorescence imaging technique was used to monitor the photosensitized processes in polystyrene (PS) and gelatin (GE) nanofibers loaded with 0.1 wt % tetraphenylporphyrin (TPP) photosensitizer. The fluorescence decay of TPP at the periphery of the PS nanofibers was single exponential. Increased fluorescence quenching was observed in the domains with higher TPP loading, located in the center of the nanofibers, and added a shorter lifetime component to the kinetics. The domains exhibiting singlet oxygen activity within the nanofibers were visualized and analyzed by singlet oxygen-sensitized delayed fluorescence imaging (SODF). Whereas O2(1deltag) was produced in PS nanofibers, its production in GE nanofibers was limited. These results were confirmed by time-resolved phosphorescence measurements at 1270 nm.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CA - Anorganická chemie
OECD FORD obor
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Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Ostatní
Rok uplatnění
2010
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Journal of Physical Chemistry B
ISSN
1520-6106
e-ISSN
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Svazek periodika
114
Číslo periodika v rámci svazku
48
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
7
Strana od-do
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Kód UT WoS článku
000284738800006
EID výsledku v databázi Scopus
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