Electroanalysis of some catecholamines at a single-wall nanotubes modified carbon paste electrode

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F10%3A10111330" target="_blank" >RIV/00216208:11310/10:10111330 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1135/cccc2010076" target="_blank" >http://dx.doi.org/10.1135/cccc2010076</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1135/cccc2010076" target="_blank" >10.1135/cccc2010076</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Electroanalysis of some catecholamines at a single-wall nanotubes modified carbon paste electrode

Popis výsledku v původním jazyce

Catecholamines (CAs) are important neurotransmitters and hormones in mammalian species. They are highly reactive and are readily oxidized to aminochromes. That enables the use of electrochemical method for their determination. In this paper, differentialpulse voltammetric (DPV) determination and HPLC with amperometric detection of dopamine (D), epinephrine (E), norepinephrine (NE) and L-Dopa (DOPA) is developed and optimized. The carbon paste electrode (CPE) prepared of carbon powder CR2 and single-wall carbon nanotubes (SWCNT) (50:50 m/m) was used. The miniaturized body for CPE was used to reduce consumption of all chemicals. In Britton-Robinson buffer solution pH 6, the limits of detection 1 x 10(-6), 2 x 10(-6), 2 x 10(-6) and 8 x 10(-6) mol dm(-3)have been found for DPV determination of D, E, NE and DOPA, respectively. HPLC was carried out using 0.1 M phosphate buffer pH 3: methanol (95: 5) mobile phase containing 10 mM EDTA. The above described CPE in a wall-jet arrangement was

Název v anglickém jazyce

Electroanalysis of some catecholamines at a single-wall nanotubes modified carbon paste electrode

Popis výsledku anglicky

Catecholamines (CAs) are important neurotransmitters and hormones in mammalian species. They are highly reactive and are readily oxidized to aminochromes. That enables the use of electrochemical method for their determination. In this paper, differentialpulse voltammetric (DPV) determination and HPLC with amperometric detection of dopamine (D), epinephrine (E), norepinephrine (NE) and L-Dopa (DOPA) is developed and optimized. The carbon paste electrode (CPE) prepared of carbon powder CR2 and single-wall carbon nanotubes (SWCNT) (50:50 m/m) was used. The miniaturized body for CPE was used to reduce consumption of all chemicals. In Britton-Robinson buffer solution pH 6, the limits of detection 1 x 10(-6), 2 x 10(-6), 2 x 10(-6) and 8 x 10(-6) mol dm(-3)have been found for DPV determination of D, E, NE and DOPA, respectively. HPLC was carried out using 0.1 M phosphate buffer pH 3: methanol (95: 5) mobile phase containing 10 mM EDTA. The above described CPE in a wall-jet arrangement was

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CG - Elektrochemie

OECD FORD obor

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Projekt

<a href="/cs/project/LC06035" target="_blank" >LC06035: Centrum biofyzikální chemie, bioelektrochemie a bioanalýzy. Nové nástroje pro genomiku, proteomiku a biomedicínu.</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Collection of Czechoslovak Chemical Communications

ISSN

0010-0765

e-ISSN

—

Svazek periodika

75

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

12

Strana od-do

1217-1228

Kód UT WoS článku

000285770100001

EID výsledku v databázi Scopus

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