Tom40 is likely common to all mitochondria

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10123206" target="_blank" >RIV/00216208:11310/12:10123206 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0960982212003442" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0960982212003442</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.cub.2012.03.057" target="_blank" >10.1016/j.cub.2012.03.057</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Tom40 is likely common to all mitochondria

Popis výsledku v původním jazyce

The evolution of the mitochondrion has involved the remodelling of the two membranes that enclose this organelle. During the transformation of the endosymbiotic bacterium into a genetically dependent organelle, the flow of proteins across the membranes reversed. This change is reflected by the distinct sets of protein transport machinery that operate in bacterial and mitochondrial membranes [1]. One of the exceptions is a ?-barrel assembly machine, Sam50, a member of the Omp85 superfamily of proteins, which has been retained in the mitochondrial membranes. Other core components of mitochondrial translocases, such as Tom40 in the outer membrane and the Tim17 family of proteins in the inner membrane, cannot be directly related to any bacterial proteins.Two studies by Pusnik et al. recently showed that the mitochondrion of Trypanosoma brucei was found to be devoid of the essential Tom40 channel [2]; instead, it was found to contain an essential protein called the archaic translocase of t

Název v anglickém jazyce

Tom40 is likely common to all mitochondria

Popis výsledku anglicky

The evolution of the mitochondrion has involved the remodelling of the two membranes that enclose this organelle. During the transformation of the endosymbiotic bacterium into a genetically dependent organelle, the flow of proteins across the membranes reversed. This change is reflected by the distinct sets of protein transport machinery that operate in bacterial and mitochondrial membranes [1]. One of the exceptions is a ?-barrel assembly machine, Sam50, a member of the Omp85 superfamily of proteins, which has been retained in the mitochondrial membranes. Other core components of mitochondrial translocases, such as Tom40 in the outer membrane and the Tim17 family of proteins in the inner membrane, cannot be directly related to any bacterial proteins.Two studies by Pusnik et al. recently showed that the mitochondrion of Trypanosoma brucei was found to be devoid of the essential Tom40 channel [2]; instead, it was found to contain an essential protein called the archaic translocase of t

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Current Biology

ISSN

0960-9822

e-ISSN

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Svazek periodika

22

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

3

Strana od-do

"R479"-"R481"

Kód UT WoS článku

000305766900006

EID výsledku v databázi Scopus

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