The Arabian Cradle: Mitochondrial Relicts of the First Steps along the Southern Route out of Africa

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10124524" target="_blank" >RIV/00216208:11310/12:10124524 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ajhg.2011.12.010" target="_blank" >http://dx.doi.org/10.1016/j.ajhg.2011.12.010</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ajhg.2011.12.010" target="_blank" >10.1016/j.ajhg.2011.12.010</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The Arabian Cradle: Mitochondrial Relicts of the First Steps along the Southern Route out of Africa

Popis výsledku v původním jazyce

A major unanswered question regarding the dispersal of modem humans around the world concerns the geographical site of the first human steps outside of Africa. The "southern coastal route" model predicts that: the early stages of the dispersal took placewhen people crossed the Red Sea to southern Arabia, but genetic evidence has hitherto been tenuous. We have addressed this question by analyzing the three minor west-Eurasian haplogroups, N1, N2, and X. These lineages branch directly from the first non-African founder node, the root of haplogroup N, and coalesce to the time of the first successful movement of modern humans out of Africa, similar to 60 thousand years (ka) ago. We sequenced complete mtDNA genomes from 85 Southwest Asian samples carryingthese haplogroups and compared them with a database of 300 European examples. The results show that these minor haplogroups have a relict distribution that suggests an ancient ancestry within the Arabian Peninsula, and they most likely sp

Název v anglickém jazyce

The Arabian Cradle: Mitochondrial Relicts of the First Steps along the Southern Route out of Africa

Popis výsledku anglicky

A major unanswered question regarding the dispersal of modem humans around the world concerns the geographical site of the first human steps outside of Africa. The "southern coastal route" model predicts that: the early stages of the dispersal took placewhen people crossed the Red Sea to southern Arabia, but genetic evidence has hitherto been tenuous. We have addressed this question by analyzing the three minor west-Eurasian haplogroups, N1, N2, and X. These lineages branch directly from the first non-African founder node, the root of haplogroup N, and coalesce to the time of the first successful movement of modern humans out of Africa, similar to 60 thousand years (ka) ago. We sequenced complete mtDNA genomes from 85 Southwest Asian samples carryingthese haplogroups and compared them with a database of 300 European examples. The results show that these minor haplogroups have a relict distribution that suggests an ancient ancestry within the Arabian Peninsula, and they most likely sp

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

AC - Archeologie, antropologie, etnologie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

AMERICAN JOURNAL OF HUMAN GENETICS

ISSN

0002-9297

e-ISSN

—

Svazek periodika

90

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

347-355

Kód UT WoS článku

000300742200017

EID výsledku v databázi Scopus

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