Genome-wide architecture of reproductive isolation in a naturally occurring hybrid zone between Mus musculus musculus and M. m. domesticus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10129944" target="_blank" >RIV/00216208:11310/12:10129944 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68081766:_____/12:00376898 RIV/67985904:_____/12:00376898

Výsledek na webu

<a href="http://dx.doi.org/10.1111/j.1365-294X.2012.05583.x" target="_blank" >http://dx.doi.org/10.1111/j.1365-294X.2012.05583.x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/j.1365-294X.2012.05583.x" target="_blank" >10.1111/j.1365-294X.2012.05583.x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Genome-wide architecture of reproductive isolation in a naturally occurring hybrid zone between Mus musculus musculus and M. m. domesticus

Popis výsledku v původním jazyce

Studies of a hybrid zone between two house mouse subspecies (Mus musculus musculus and M. m. domesticus) along with studies using laboratory crosses reveal a large role for the X chromosome and multiple autosomal regions in reproductive isolation as a consequence of disrupted epistasis in hybrids. One limitation of previous work has been that most of the identified genomic regions have been large. The goal here is to detect and characterize precise genomic regions underlying reproductive isolation. We surveyed 1401 markers evenly spaced across the genome in 679 mice collected from two different transects. Comparisons between transects provide a means for identifying common patterns that likely reflect intrinsic incompatibilities. We used a genomic cline approach to identify patterns that correspond to epistasis. From both transects,we identified contiguous regions on the X chromosome in which markers were inferred to be involved in epistatic interactions.Wethen searched for autosomal r

Název v anglickém jazyce

Genome-wide architecture of reproductive isolation in a naturally occurring hybrid zone between Mus musculus musculus and M. m. domesticus

Popis výsledku anglicky

Studies of a hybrid zone between two house mouse subspecies (Mus musculus musculus and M. m. domesticus) along with studies using laboratory crosses reveal a large role for the X chromosome and multiple autosomal regions in reproductive isolation as a consequence of disrupted epistasis in hybrids. One limitation of previous work has been that most of the identified genomic regions have been large. The goal here is to detect and characterize precise genomic regions underlying reproductive isolation. We surveyed 1401 markers evenly spaced across the genome in 679 mice collected from two different transects. Comparisons between transects provide a means for identifying common patterns that likely reflect intrinsic incompatibilities. We used a genomic cline approach to identify patterns that correspond to epistasis. From both transects,we identified contiguous regions on the X chromosome in which markers were inferred to be involved in epistatic interactions.Wethen searched for autosomal r

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EG - Zoologie

OECD FORD obor

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Projekt

<a href="/cs/project/GA206%2F08%2F0640" target="_blank" >GA206/08/0640: Immunogenetické studium hybridní zóny myší domácích</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Molecular Ecology

ISSN

0962-1083

e-ISSN

—

Svazek periodika

21

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

16

Strana od-do

3032-3047

Kód UT WoS článku

000304903100019

EID výsledku v databázi Scopus

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