Rapidly Developing Yeast Microcolonies Differentiate in a Similar Way to Aging Giant Colonies
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10138862" target="_blank" >RIV/00216208:11310/13:10138862 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61388971:_____/13:00425474
Výsledek na webu
<a href="http://www.hindawi.com/journals/oximed/2013/102485/" target="_blank" >http://www.hindawi.com/journals/oximed/2013/102485/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2013/102485" target="_blank" >10.1155/2013/102485</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Rapidly Developing Yeast Microcolonies Differentiate in a Similar Way to Aging Giant Colonies
Popis výsledku v původním jazyce
During their development and aging on solid substrates, yeast giant colonies produce ammonia, which acts as a quorum sensing molecule. Ammonia production is connected with alkalization of the surrounding medium and with extensive reprogramming of cell metabolism. In addition, ammonia signaling is important for both horizontal (colony centre versus colony margin) and vertical (upper versus lower cell layers) colony differentiations. The centre of an aging differentiated giant colony is thus composed of two major cell subpopulations, the subpopulation of long-living, metabolically active and stress-resistant cells that form the upper layers of the colony and the subpopulation of stress-sensitive starving cells in the colony interior. Here, we show that microcolonies originating from one cell pass through similar developmental phases as giant colonies. Microcolony differentiation is linked to ammonia signaling, and cells similar to the upper and lower cells of aged giant colonies are form
Název v anglickém jazyce
Rapidly Developing Yeast Microcolonies Differentiate in a Similar Way to Aging Giant Colonies
Popis výsledku anglicky
During their development and aging on solid substrates, yeast giant colonies produce ammonia, which acts as a quorum sensing molecule. Ammonia production is connected with alkalization of the surrounding medium and with extensive reprogramming of cell metabolism. In addition, ammonia signaling is important for both horizontal (colony centre versus colony margin) and vertical (upper versus lower cell layers) colony differentiations. The centre of an aging differentiated giant colony is thus composed of two major cell subpopulations, the subpopulation of long-living, metabolically active and stress-resistant cells that form the upper layers of the colony and the subpopulation of stress-sensitive starving cells in the colony interior. Here, we show that microcolonies originating from one cell pass through similar developmental phases as giant colonies. Microcolony differentiation is linked to ammonia signaling, and cells similar to the upper and lower cells of aged giant colonies are form
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
EE - Mikrobiologie, virologie
OECD FORD obor
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Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2013
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Oxidative Medicine and Cellular Longevity
ISSN
1942-0900
e-ISSN
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Svazek periodika
2013
Číslo periodika v rámci svazku
Accepted 25 June 2013
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
9
Strana od-do
1-9
Kód UT WoS článku
000322655100001
EID výsledku v databázi Scopus
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