Surfactin production enhances the level of cardiolipin in the cytoplasmic membrane of Bacillus subtilis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10159281" target="_blank" >RIV/00216208:11310/13:10159281 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61388971:_____/13:00426295

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.bbamem.2013.06.032" target="_blank" >http://dx.doi.org/10.1016/j.bbamem.2013.06.032</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.bbamem.2013.06.032" target="_blank" >10.1016/j.bbamem.2013.06.032</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Surfactin production enhances the level of cardiolipin in the cytoplasmic membrane of Bacillus subtilis

Popis výsledku v původním jazyce

Surfactin is a cyclic lipopeptide antibiotic that disturbs the integrity of the cytoplasmic membrane. In this study, the role of membrane lipids in the adaptation and possible surfactin tolerance of the surfactin producer Bacillus subtilis ATCC 21332 wasinvestigated. During a 1-day cultivation, the phospholipids of the cell membrane were analyzed at the selected time points, which covered both the early and late stationary phases of growth, when surfactin concentration in the medium gradually rose from2 to 84 mu mol.l(-1). During this time period, the phospholipid composition of the surfactin producer's membrane (Sf(+)) was compared to that of its non-producing mutant (Sf(-)). Substantial modifications of the polar head group region in response to the presence of surfactin were found, while the fatty acid content remained unaffected. Simultaneously with surfactin production, a progressive accumulation up to 22% of the stress phospholipid cardiolipin was determined in the Sf+ membrane

Název v anglickém jazyce

Surfactin production enhances the level of cardiolipin in the cytoplasmic membrane of Bacillus subtilis

Popis výsledku anglicky

Surfactin is a cyclic lipopeptide antibiotic that disturbs the integrity of the cytoplasmic membrane. In this study, the role of membrane lipids in the adaptation and possible surfactin tolerance of the surfactin producer Bacillus subtilis ATCC 21332 wasinvestigated. During a 1-day cultivation, the phospholipids of the cell membrane were analyzed at the selected time points, which covered both the early and late stationary phases of growth, when surfactin concentration in the medium gradually rose from2 to 84 mu mol.l(-1). During this time period, the phospholipid composition of the surfactin producer's membrane (Sf(+)) was compared to that of its non-producing mutant (Sf(-)). Substantial modifications of the polar head group region in response to the presence of surfactin were found, while the fatty acid content remained unaffected. Simultaneously with surfactin production, a progressive accumulation up to 22% of the stress phospholipid cardiolipin was determined in the Sf+ membrane

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biochimica et Biophysica Acta - Biomembranes

ISSN

0005-2736

e-ISSN

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Svazek periodika

1828

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

9

Strana od-do

2370-2378

Kód UT WoS článku

000326143200002

EID výsledku v databázi Scopus

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