The Growth and Delivery of Mezenchymal and Limbal Stem Cells Using Copolymer Polyamide 6/12 Nanofiber Scaffold

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10190914" target="_blank" >RIV/00216208:11310/13:10190914 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/978-1-62703-432-6_13" target="_blank" >http://dx.doi.org/10.1007/978-1-62703-432-6_13</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-1-62703-432-6_13" target="_blank" >10.1007/978-1-62703-432-6_13</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The Growth and Delivery of Mezenchymal and Limbal Stem Cells Using Copolymer Polyamide 6/12 Nanofiber Scaffold

Popis výsledku v původním jazyce

The injured or otherwise damaged cornea is healed by limbal stem cells (LSC). If the limbus where LSC reside is also damaged or nonfunctional, the cornea cannot heal properly and this defect leads to impaired vision that can result in blindness. The onlyway to treat total LSC deficiency is by transplantation of limbal tissue or a transfer of LSC. Recently, mesenchymal stem cells (MSC) have been shown as another promising source of stem cells for corneal healing and regeneration. Here, we describe a protocol for the use of polyamide 6/12 nanofiber scaffolds for the growth of MSC and LSC, and for their transfer onto a mechanically damaged ocular surface in the experimental mouse model.

Název v anglickém jazyce

The Growth and Delivery of Mezenchymal and Limbal Stem Cells Using Copolymer Polyamide 6/12 Nanofiber Scaffold

Popis výsledku anglicky

The injured or otherwise damaged cornea is healed by limbal stem cells (LSC). If the limbus where LSC reside is also damaged or nonfunctional, the cornea cannot heal properly and this defect leads to impaired vision that can result in blindness. The onlyway to treat total LSC deficiency is by transplantation of limbal tissue or a transfer of LSC. Recently, mesenchymal stem cells (MSC) have been shown as another promising source of stem cells for corneal healing and regeneration. Here, we describe a protocol for the use of polyamide 6/12 nanofiber scaffolds for the growth of MSC and LSC, and for their transfer onto a mechanically damaged ocular surface in the experimental mouse model.

Druh

C - Kapitola v odborné knize

CEP obor

EC - Imunologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Corneal Regenerative Medicine

ISBN

978-1-62703-431-9

Počet stran výsledku

13

Strana od-do

187-199

Počet stran knihy

230

Název nakladatele

Humana Press

Místo vydání

New York

Kód UT WoS kapitoly

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