Nonaqueous emulsion polymerization: A practical synthetic route for the production of molecularly imprinted nanospheres

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10191296" target="_blank" >RIV/00216208:11310/13:10191296 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/pola.26402" target="_blank" >http://dx.doi.org/10.1002/pola.26402</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/pola.26402" target="_blank" >10.1002/pola.26402</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Nonaqueous emulsion polymerization: A practical synthetic route for the production of molecularly imprinted nanospheres

Popis výsledku v původním jazyce

Monodisperse, molecularly imprinted nanospheres were synthesized by nonaqueous (mini)emulsion polymerization using a standard monomer mixture of methacrylic acid and ethylene dimethacrylate containing the drug propranolol as a template. The preparation conditions (solvent, amount of surfactant, and amount of employed template) were extensively varied in order to assess their effect on the properties of the resulting polymer nanoparticles. The molecular recognition capability of the nanospheres was evaluated in batch rebinding experiments, and the effect of the nanosphere preparation conditions as well as of the reaction conditions was investigated. In this way, optimal preparation protocols for molecularly imprinted nanoparticles under nonaqueous conditions with the use of a nonionic emulsifier were identified, which lead to nanospheres with a diameter of around 100 nm having an enhanced capacity of specific template rebinding compared to both nonimprinted nanospheres and to particles

Název v anglickém jazyce

Nonaqueous emulsion polymerization: A practical synthetic route for the production of molecularly imprinted nanospheres

Popis výsledku anglicky

Monodisperse, molecularly imprinted nanospheres were synthesized by nonaqueous (mini)emulsion polymerization using a standard monomer mixture of methacrylic acid and ethylene dimethacrylate containing the drug propranolol as a template. The preparation conditions (solvent, amount of surfactant, and amount of employed template) were extensively varied in order to assess their effect on the properties of the resulting polymer nanoparticles. The molecular recognition capability of the nanospheres was evaluated in batch rebinding experiments, and the effect of the nanosphere preparation conditions as well as of the reaction conditions was investigated. In this way, optimal preparation protocols for molecularly imprinted nanoparticles under nonaqueous conditions with the use of a nonionic emulsifier were identified, which lead to nanospheres with a diameter of around 100 nm having an enhanced capacity of specific template rebinding compared to both nonimprinted nanospheres and to particles

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CD - Makromolekulární chemie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Polymer Science, Part A: Polymer Chemistry

ISSN

0887-624X

e-ISSN

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Svazek periodika

51

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

8

Strana od-do

267-274

Kód UT WoS článku

000312448800005

EID výsledku v databázi Scopus

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