A Large Pseudoautosomal Region on the Sex Chromosomes of the Frog Silurana tropicalis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10191641" target="_blank" >RIV/00216208:11310/13:10191641 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00027162:_____/13:#0001028

Výsledek na webu

<a href="http://dx.doi.org/10.1093/gbe/evt073" target="_blank" >http://dx.doi.org/10.1093/gbe/evt073</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/gbe/evt073" target="_blank" >10.1093/gbe/evt073</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A Large Pseudoautosomal Region on the Sex Chromosomes of the Frog Silurana tropicalis

Popis výsledku v původním jazyce

Sex chromosome divergence has been documented across phylogenetically diverse species, with amphibians typically having cytologically nondiverged ("homomorphic") sex chromosomes. With an aim of further characterizing sex chromosome divergence of an amphibian, we used "RAD-tags" and Sanger sequencing to examine sex specificity and heterozygosity in the Western clawed frog Silurana tropicalis (also known as Xenopus tropicalis). Our findings based on approximately 20 million genotype calls and approximately 200 polymerase chain reaction-amplified regions across multiple male and female genomes failed to identify a substantially sized genomic region with genotypic hallmarks of sex chromosome divergence, including in regions known to be tightly linked to the sex-determining region. We also found that expression and molecular evolution of genes linked to the sex-determining region did not differ substantially from genes in other parts of the genome. This suggests that the pseudoautosomal reg

Název v anglickém jazyce

A Large Pseudoautosomal Region on the Sex Chromosomes of the Frog Silurana tropicalis

Popis výsledku anglicky

Sex chromosome divergence has been documented across phylogenetically diverse species, with amphibians typically having cytologically nondiverged ("homomorphic") sex chromosomes. With an aim of further characterizing sex chromosome divergence of an amphibian, we used "RAD-tags" and Sanger sequencing to examine sex specificity and heterozygosity in the Western clawed frog Silurana tropicalis (also known as Xenopus tropicalis). Our findings based on approximately 20 million genotype calls and approximately 200 polymerase chain reaction-amplified regions across multiple male and female genomes failed to identify a substantially sized genomic region with genotypic hallmarks of sex chromosome divergence, including in regions known to be tightly linked to the sex-determining region. We also found that expression and molecular evolution of genes linked to the sex-determining region did not differ substantially from genes in other parts of the genome. This suggests that the pseudoautosomal reg

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

<a href="/cs/project/GPP502%2F11%2FP522" target="_blank" >GPP502/11/P522: Fyzické mapování genomu Xenopus tropicalis.</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Genome Biology and Evolution

ISSN

1759-6653

e-ISSN

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Svazek periodika

5

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

12

Strana od-do

1087-1098

Kód UT WoS článku

000324594100005

EID výsledku v databázi Scopus

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