Common mechanisms of pain and depression: are antidepressants also analgesics?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10218702" target="_blank" >RIV/00216208:11310/14:10218702 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985823:_____/14:00427829 RIV/00216208:11110/14:10218702 RIV/00216208:11120/14:43908389 RIV/00064165:_____/14:10218702

Výsledek na webu

<a href="http://dx.doi.org/10.3389/fnbeh.2014.00099" target="_blank" >http://dx.doi.org/10.3389/fnbeh.2014.00099</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fnbeh.2014.00099" target="_blank" >10.3389/fnbeh.2014.00099</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Common mechanisms of pain and depression: are antidepressants also analgesics?

Popis výsledku v původním jazyce

Neither pain, nor depression exist as Independent phenomena per se, they are highly subjective inner states, formed by our brain and built on the bases of our experiences, cognition and emotions. Chronic pain is associated with changes in brain physiology and anatomy. It has been suggested that the neuronal activity underlying subjective perception of chronic pain may be divergent from the activity associated with acute pain. We will discuss the possible common pathophysiological mechanism of chronic pain and depression with respect to the default mode network of the brain, neuroplasticity and the effect of antidepressants on these two pathological conditions. The default mode network of the brain has an important role in the representation of introspective mental activities and therefore can be considered as a nodal point, common for both chronic pain and depression. Neuroplasticity which involves molecular, cellular and synaptic processes modifying connectivity between neurons and ne

Název v anglickém jazyce

Common mechanisms of pain and depression: are antidepressants also analgesics?

Popis výsledku anglicky

Neither pain, nor depression exist as Independent phenomena per se, they are highly subjective inner states, formed by our brain and built on the bases of our experiences, cognition and emotions. Chronic pain is associated with changes in brain physiology and anatomy. It has been suggested that the neuronal activity underlying subjective perception of chronic pain may be divergent from the activity associated with acute pain. We will discuss the possible common pathophysiological mechanism of chronic pain and depression with respect to the default mode network of the brain, neuroplasticity and the effect of antidepressants on these two pathological conditions. The default mode network of the brain has an important role in the representation of introspective mental activities and therefore can be considered as a nodal point, common for both chronic pain and depression. Neuroplasticity which involves molecular, cellular and synaptic processes modifying connectivity between neurons and ne

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Frontiers in Behavioral Neuroscience

ISSN

1662-5153

e-ISSN

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Svazek periodika

8

Číslo periodika v rámci svazku

Mar 25

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

12

Strana od-do

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Kód UT WoS článku

000333330000001

EID výsledku v databázi Scopus

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