The exocyst at the interface between cytoskeleton and membranes in eukaryotic cells
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10281640" target="_blank" >RIV/00216208:11310/14:10281640 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61389030:_____/14:00429989
Výsledek na webu
<a href="http://dx.doi.org/10.3389/fpls.2013.00543" target="_blank" >http://dx.doi.org/10.3389/fpls.2013.00543</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fpls.2013.00543" target="_blank" >10.3389/fpls.2013.00543</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The exocyst at the interface between cytoskeleton and membranes in eukaryotic cells
Popis výsledku v původním jazyce
Delivery and final fusion of the secretory vesicles with the relevant target membrane are hierarchically organized and reciprocally interconnected multi-step processes involving not only specific protein protein interactions, but also specific protein phospholipid interactions. The exocyst was discovered as a tethering complex mediating initial encounter of arriving exocytic vesicles with the plasma membrane. The exocyst complex is regulated by Rab and Rho small GTPases, resulting in docking of exocyticvesicles to the plasma membrane (PM) and finally their fusion mediated by specific SNARE complexes. In model Opisthokont cells, the exocyst was shown to directly interact with both microtubule and microfilament cytoskeleton and related motor proteins aswell as with the PM via phosphatidylinositol 4,5-bisphosphate specific binding, which directly affects cortical cytoskeleton and PM dynamics. Here we summarize the current knowledge on exocyst-cytoskeleton-PM interactions in order to ope
Název v anglickém jazyce
The exocyst at the interface between cytoskeleton and membranes in eukaryotic cells
Popis výsledku anglicky
Delivery and final fusion of the secretory vesicles with the relevant target membrane are hierarchically organized and reciprocally interconnected multi-step processes involving not only specific protein protein interactions, but also specific protein phospholipid interactions. The exocyst was discovered as a tethering complex mediating initial encounter of arriving exocytic vesicles with the plasma membrane. The exocyst complex is regulated by Rab and Rho small GTPases, resulting in docking of exocyticvesicles to the plasma membrane (PM) and finally their fusion mediated by specific SNARE complexes. In model Opisthokont cells, the exocyst was shown to directly interact with both microtubule and microfilament cytoskeleton and related motor proteins aswell as with the PM via phosphatidylinositol 4,5-bisphosphate specific binding, which directly affects cortical cytoskeleton and PM dynamics. Here we summarize the current knowledge on exocyst-cytoskeleton-PM interactions in order to ope
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
EB - Genetika a molekulární biologie
OECD FORD obor
—
Návaznosti výsledku
Projekt
<a href="/cs/project/GPP501%2F11%2FP853" target="_blank" >GPP501/11/P853: The exocyst, secretory vesicles tethering complex, in auxin transport polarization</a><br>
Návaznosti
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Frontiers in Plant Science
ISSN
1664-462X
e-ISSN
—
Svazek periodika
4
Číslo periodika v rámci svazku
JAN
Stát vydavatele periodika
CH - Švýcarská konfederace
Počet stran výsledku
7
Strana od-do
—
Kód UT WoS článku
000331525300001
EID výsledku v databázi Scopus
—