Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10297177" target="_blank" >RIV/00216208:11310/15:10297177 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1186/s13071-015-0976-1" target="_blank" >http://dx.doi.org/10.1186/s13071-015-0976-1</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s13071-015-0976-1" target="_blank" >10.1186/s13071-015-0976-1</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia

Popis výsledku v původním jazyce

Background: Human visceral leishmaniasis caused by Leishmania donovani is considered an anthroponosis; however, Leishmania-infected animals have been increasingly reported in L. donovani foci, and the role of these animals as reservoirs for human L. donovani infection remains unclear. Methods: We conducted a study of domestic animals (goats, sheep, cows, dogs, and donkeys) in three L. donovani foci in northwestern Ethiopia. Domestic animals were screened for Leishmania DNA and for anti-L. donovani IgG.Serum anti-sand fly saliva antibodies were used as a marker of exposure to the vector sand fly, Phlebotomus orientalis. Results: Of 546 animals tested, 32 (5.9 %) were positive for Leishmania DNA, with positive animals identified among all species studied. Sequencing indicated that the animals were infected with parasites of the L. donovani complex but could not distinguish between L. infantum and L. donovani. A total of 18.9 % of the animals were seropositive for anti-L. donovani IgG, a

Název v anglickém jazyce

Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia

Popis výsledku anglicky

Background: Human visceral leishmaniasis caused by Leishmania donovani is considered an anthroponosis; however, Leishmania-infected animals have been increasingly reported in L. donovani foci, and the role of these animals as reservoirs for human L. donovani infection remains unclear. Methods: We conducted a study of domestic animals (goats, sheep, cows, dogs, and donkeys) in three L. donovani foci in northwestern Ethiopia. Domestic animals were screened for Leishmania DNA and for anti-L. donovani IgG.Serum anti-sand fly saliva antibodies were used as a marker of exposure to the vector sand fly, Phlebotomus orientalis. Results: Of 546 animals tested, 32 (5.9 %) were positive for Leishmania DNA, with positive animals identified among all species studied. Sequencing indicated that the animals were infected with parasites of the L. donovani complex but could not distinguish between L. infantum and L. donovani. A total of 18.9 % of the animals were seropositive for anti-L. donovani IgG, a

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EG - Zoologie

OECD FORD obor

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Projekt

<a href="/cs/project/GA13-05292S" target="_blank" >GA13-05292S: Proteiny slinných žlaz Phlebotomus orientalis a protilátková odpověď pobodaných hostitelů</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Parasites and Vectors

ISSN

1756-3305

e-ISSN

—

Svazek periodika

8

Číslo periodika v rámci svazku

July 8, 2015

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

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Kód UT WoS článku

000357470300003

EID výsledku v databázi Scopus

2-s2.0-84935479188