Interstitial Telomeric Motifs in Squamate Reptiles: When the Exceptions Outnumber the Rule

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10312684" target="_blank" >RIV/00216208:11310/15:10312684 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985904:_____/15:00454215

Výsledek na webu

<a href="http://dx.doi.org/10.1371/journal.pone.0134985" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0134985</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1371/journal.pone.0134985" target="_blank" >10.1371/journal.pone.0134985</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Interstitial Telomeric Motifs in Squamate Reptiles: When the Exceptions Outnumber the Rule

Popis výsledku v původním jazyce

Telomeres are nucleoprotein complexes protecting the physical ends of linear eukaryotic chromosomes and therefore helping to ensure their stability and integrity. Additionally, telomeric sequences can be localized in non-terminal regions of chromosomes,forming so-called interstitial telomeric sequences (ITSs). ITSs are traditionally considered to be relics of chromosomal rearrangements and thus very informative in the reconstruction of the evolutionary history of karyotype formation. We examined the distribution of the telomeric motifs (TTAGGG)(n) using fluorescence in situ hybridization (FISH) in 30 species, representing 17 families of squamate reptiles, and compared them with the collected data from another 38 species from literature. Out of the 68squamate species analyzed, 35 possess ITSs in pericentromeric regions, centromeric regions and/or within chromosome arms. We conclude that the occurrence of ITSs is rather common in squamates, despite their generally conserved karyotypes,

Název v anglickém jazyce

Interstitial Telomeric Motifs in Squamate Reptiles: When the Exceptions Outnumber the Rule

Popis výsledku anglicky

Telomeres are nucleoprotein complexes protecting the physical ends of linear eukaryotic chromosomes and therefore helping to ensure their stability and integrity. Additionally, telomeric sequences can be localized in non-terminal regions of chromosomes,forming so-called interstitial telomeric sequences (ITSs). ITSs are traditionally considered to be relics of chromosomal rearrangements and thus very informative in the reconstruction of the evolutionary history of karyotype formation. We examined the distribution of the telomeric motifs (TTAGGG)(n) using fluorescence in situ hybridization (FISH) in 30 species, representing 17 families of squamate reptiles, and compared them with the collected data from another 38 species from literature. Out of the 68squamate species analyzed, 35 possess ITSs in pericentromeric regions, centromeric regions and/or within chromosome arms. We conclude that the occurrence of ITSs is rather common in squamates, despite their generally conserved karyotypes,

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EG - Zoologie

OECD FORD obor

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Projekt

<a href="/cs/project/GAP506%2F10%2F0718" target="_blank" >GAP506/10/0718: Evoluce pohlavně determinačních mechanismů šupinatých plazů: molekulárně cytogenetický test nezávislého vzniku pohlavních chromozomů</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

PLoS ONE

ISSN

1932-6203

e-ISSN

—

Svazek periodika

10

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

14

Strana od-do

—

Kód UT WoS článku

000359121100098

EID výsledku v databázi Scopus

2-s2.0-84942133558