Worse Health Status and Higher Incidence of Health Disorders in Rhesus Negative Subjects

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10317368" target="_blank" >RIV/00216208:11310/15:10317368 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00023884:_____/15:#0007162

Výsledek na webu

<a href="http://dx.doi.org/10.1371/journal.pone.0141362" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0141362</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1371/journal.pone.0141362" target="_blank" >10.1371/journal.pone.0141362</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Worse Health Status and Higher Incidence of Health Disorders in Rhesus Negative Subjects

Popis výsledku v původním jazyce

Rhesus-positive and Rhesus-negative persons differ in the presence-absence of highly immunogenic RhD protein on the erythrocyte membrane. The biological function of the RhD molecule is unknown. Its structure suggests that the molecular complex with RhD protein transports NH3 or CO2 molecules across the erythrocyte cell membrane. Some data indicate that RhD positive and RhD negative subjects differ in their tolerance to certain biological factors, including, Toxoplasma infection, aging and fatique. Present cross sectional study performed on 3,130 subjects) showed that Rhesus negative subjects differed in many indices of their health status, including incidences of many disorders. Rhesus negative subjects reported to have more frequent allergic, digestive, heart, hematological, immunity, mental health, and neurological problems. On the population level, a Rhesus-negativity-associated burden could be compensated for, for example, by the heterozygote advantage, but for Rhesus negative subj

Název v anglickém jazyce

Worse Health Status and Higher Incidence of Health Disorders in Rhesus Negative Subjects

Popis výsledku anglicky

Rhesus-positive and Rhesus-negative persons differ in the presence-absence of highly immunogenic RhD protein on the erythrocyte membrane. The biological function of the RhD molecule is unknown. Its structure suggests that the molecular complex with RhD protein transports NH3 or CO2 molecules across the erythrocyte cell membrane. Some data indicate that RhD positive and RhD negative subjects differ in their tolerance to certain biological factors, including, Toxoplasma infection, aging and fatique. Present cross sectional study performed on 3,130 subjects) showed that Rhesus negative subjects differed in many indices of their health status, including incidences of many disorders. Rhesus negative subjects reported to have more frequent allergic, digestive, heart, hematological, immunity, mental health, and neurological problems. On the population level, a Rhesus-negativity-associated burden could be compensated for, for example, by the heterozygote advantage, but for Rhesus negative subj

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

—

Projekt

<a href="/cs/project/GAP303%2F11%2F1398" target="_blank" >GAP303/11/1398: Úleková reakce a prepulsní inhibice u lidí s latentní toxoplasmosou</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

PLoS ONE

ISSN

1932-6203

e-ISSN

—

Svazek periodika

10

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

14

Strana od-do

—

Kód UT WoS článku

000363309200103

EID výsledku v databázi Scopus

2-s2.0-84949844911