Chlorpyrifos-methyl oxon hydrolysis and its monitoring by HPLC-MS/MS

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F18%3A10378573" target="_blank" >RIV/00216208:11310/18:10378573 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1007/s00706-018-2219-6" target="_blank" >https://doi.org/10.1007/s00706-018-2219-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00706-018-2219-6" target="_blank" >10.1007/s00706-018-2219-6</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Chlorpyrifos-methyl oxon hydrolysis and its monitoring by HPLC-MS/MS

Popis výsledku v původním jazyce

Organophosphates belong to a family of acetylcholinesterase inhibiting neurotoxins. The toxicity of the parent compound, e.g., chlorpyrifos-methyl is usually tested. However, the toxicity of its transformation products and the transformation process itself are often overlooked. The chlorpyrifos-methyl oxon degradation reaction was monitored using the newly developed, reversed phase high-performance liquid chromatography methods with tandem mass spectrometry detection. These methods were applied to examine chlorpyrifos-methyl oxon hydrolysis at pH 9.2 and at 40 A degrees C, thereby determining the two hydrolysis products in a single, 6-min run without internal standards. The method is cheaper and less demanding than previous methods, particularly regarding sample preparation.

Název v anglickém jazyce

Chlorpyrifos-methyl oxon hydrolysis and its monitoring by HPLC-MS/MS

Popis výsledku anglicky

Organophosphates belong to a family of acetylcholinesterase inhibiting neurotoxins. The toxicity of the parent compound, e.g., chlorpyrifos-methyl is usually tested. However, the toxicity of its transformation products and the transformation process itself are often overlooked. The chlorpyrifos-methyl oxon degradation reaction was monitored using the newly developed, reversed phase high-performance liquid chromatography methods with tandem mass spectrometry detection. These methods were applied to examine chlorpyrifos-methyl oxon hydrolysis at pH 9.2 and at 40 A degrees C, thereby determining the two hydrolysis products in a single, 6-min run without internal standards. The method is cheaper and less demanding than previous methods, particularly regarding sample preparation.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Monatshefte für Chemie - Chemical Monthly

ISSN

0026-9247

e-ISSN

—

Svazek periodika

149

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

AT - Rakouská republika

Počet stran výsledku

5

Strana od-do

1515-1519

Kód UT WoS článku

000442501400003

EID výsledku v databázi Scopus

2-s2.0-85051296969