Toxoplasmosis, but not borreliosis, is associated with psychiatric disorders and symptoms

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F18%3A10392416" target="_blank" >RIV/00216208:11310/18:10392416 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00023752:_____/18:43919439

Výsledek na webu

<a href="https://doi.org/10.1016/j.schres.2018.02.008" target="_blank" >https://doi.org/10.1016/j.schres.2018.02.008</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.schres.2018.02.008" target="_blank" >10.1016/j.schres.2018.02.008</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Toxoplasmosis, but not borreliosis, is associated with psychiatric disorders and symptoms

Popis výsledku v původním jazyce

Infection by the parasite Toxoplasma, which affects about 33% of world population, is associated with increased risk of several mental health disorders, the most strongly with schizophrenia. It is unknown whether toxoplasmosis really plays a substantial role in the etiopathogenesis of these disorders and whether schizophrenia is associated with this infection the most strongly, or whether this association has just been the most intensively studied for historical reasons. We used the data from 3,440 and 7,800 subjects tested for toxoplasmosis and borreliosis, respectively, who took part in an internet survey, for searching in the associations of these infections with 22 mental health disorders and other indices of impaired mental health. The typical symptom associated with toxoplasmosis was anxiety, and the typical toxoplasmosis-associated disorders were autism (OR=4.86), schizophrenia (OR=3.34), attention deficit hyperactivity disorder (OR=3.02), Asperger syndrome (OR=2.49), antisocial personality disorder (OR=1.81), OCD (OR=1.69), and anxiety disorder (OR=1.57). Borreliosis was associated only with symptoms of depression and with major depression (OR=1.65). The negative effects of borreliosis were detectable only in the Toxoplasma-infected subjects. Toxoplasmosis could play a substantial role in the etiopathogenesis of mental health disorders and its association with schizophrenia is the second strongest association, after autism.

Název v anglickém jazyce

Toxoplasmosis, but not borreliosis, is associated with psychiatric disorders and symptoms

Popis výsledku anglicky

Infection by the parasite Toxoplasma, which affects about 33% of world population, is associated with increased risk of several mental health disorders, the most strongly with schizophrenia. It is unknown whether toxoplasmosis really plays a substantial role in the etiopathogenesis of these disorders and whether schizophrenia is associated with this infection the most strongly, or whether this association has just been the most intensively studied for historical reasons. We used the data from 3,440 and 7,800 subjects tested for toxoplasmosis and borreliosis, respectively, who took part in an internet survey, for searching in the associations of these infections with 22 mental health disorders and other indices of impaired mental health. The typical symptom associated with toxoplasmosis was anxiety, and the typical toxoplasmosis-associated disorders were autism (OR=4.86), schizophrenia (OR=3.34), attention deficit hyperactivity disorder (OR=3.02), Asperger syndrome (OR=2.49), antisocial personality disorder (OR=1.81), OCD (OR=1.69), and anxiety disorder (OR=1.57). Borreliosis was associated only with symptoms of depression and with major depression (OR=1.65). The negative effects of borreliosis were detectable only in the Toxoplasma-infected subjects. Toxoplasmosis could play a substantial role in the etiopathogenesis of mental health disorders and its association with schizophrenia is the second strongest association, after autism.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

Projekt

<a href="/cs/project/GA16-20958S" target="_blank" >GA16-20958S: Role chovu koček a psů a některých s nimi asociovaných nákaz při vzniku klinických a subklinických forem deprese, OCD, fobií a psychóz</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Schizophrenia Research

ISSN

0920-9964

e-ISSN

—

Svazek periodika

197

Číslo periodika v rámci svazku

January

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

2

Strana od-do

603-604

Kód UT WoS článku

000437786100103

EID výsledku v databázi Scopus

2-s2.0-85042081647