Interactions of star-like polyelectrolyte micelles with hydrophobic counterions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F19%3A10403719" target="_blank" >RIV/00216208:11310/19:10403719 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/19:10403719

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=bBW6rHMZ__" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=bBW6rHMZ__</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jcis.2019.03.054" target="_blank" >10.1016/j.jcis.2019.03.054</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Interactions of star-like polyelectrolyte micelles with hydrophobic counterions

Popis výsledku v původním jazyce

Hydrophobicity of a counterion has a profound effect on the interaction with polyelectrolytes similar to that of multivalency. Specifically, understanding this interaction in weak polyelectrolyte micelles might assist in developing nanocarriers for pH-controlled encapsulation and release. We used star-like weak polyelectrolyte micelles of polystyrene-block-poly(2-vinyl pyridine) (PS-P2VP) with fixed aggregation number as a model polyelectrolyte, and cobalt bis(1,2-dicarbollide) (COSAN) as a model hydrophobic anion. We used NMR to assess the mobility of the polymer segments in the presence of varying amounts of COSAN, and at varying protonation degrees of the polyelectrolyte. Same experiments with indifferent electrolyte (NaCl) were used as a control. Furthermore, we used coarse-grained simulations to obtain a detailed picture of the effect of hydrophobic counterions on the conformation of the micelles. A small amount of hydrophobic counterions causes morphological changes within the micelles, whereas a bigger amount causes precipitation. This was confirmed both in simulations and in experiments. Furthermore, adsorption of the counterions induces ionization of the collapsed segments of the polyelectrolyte. Although the COSAN/P2VP system is rather specific, the generic model used in the coarse-grained simulations shows that the observed behavior is a consequence of synergy of hydrophobic and electrostatic attraction between polyelectrolytes and hydrophobic counterions. Our study provides general insights into the molecular mechanisms of these interactions.

Název v anglickém jazyce

Interactions of star-like polyelectrolyte micelles with hydrophobic counterions

Popis výsledku anglicky

Hydrophobicity of a counterion has a profound effect on the interaction with polyelectrolytes similar to that of multivalency. Specifically, understanding this interaction in weak polyelectrolyte micelles might assist in developing nanocarriers for pH-controlled encapsulation and release. We used star-like weak polyelectrolyte micelles of polystyrene-block-poly(2-vinyl pyridine) (PS-P2VP) with fixed aggregation number as a model polyelectrolyte, and cobalt bis(1,2-dicarbollide) (COSAN) as a model hydrophobic anion. We used NMR to assess the mobility of the polymer segments in the presence of varying amounts of COSAN, and at varying protonation degrees of the polyelectrolyte. Same experiments with indifferent electrolyte (NaCl) were used as a control. Furthermore, we used coarse-grained simulations to obtain a detailed picture of the effect of hydrophobic counterions on the conformation of the micelles. A small amount of hydrophobic counterions causes morphological changes within the micelles, whereas a bigger amount causes precipitation. This was confirmed both in simulations and in experiments. Furthermore, adsorption of the counterions induces ionization of the collapsed segments of the polyelectrolyte. Although the COSAN/P2VP system is rather specific, the generic model used in the coarse-grained simulations shows that the observed behavior is a consequence of synergy of hydrophobic and electrostatic attraction between polyelectrolytes and hydrophobic counterions. Our study provides general insights into the molecular mechanisms of these interactions.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Colloid and Interface Science

ISSN

0021-9797

e-ISSN

—

Svazek periodika

546

Číslo periodika v rámci svazku

June

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

371-380

Kód UT WoS článku

000466054200037

EID výsledku v databázi Scopus

2-s2.0-85063509527