A Sensitive Sensor Based on Single-walled Carbon Nanotubes: Its Preparation, Characterization and Application in the Electrochemical Determination of Drug Clorsulon in Milk Samples

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F20%3A10409846" target="_blank" >RIV/00216208:11310/20:10409846 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Qoz.Z7hpTw" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Qoz.Z7hpTw</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/elan.201900387" target="_blank" >10.1002/elan.201900387</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A Sensitive Sensor Based on Single-walled Carbon Nanotubes: Its Preparation, Characterization and Application in the Electrochemical Determination of Drug Clorsulon in Milk Samples

Popis výsledku v původním jazyce

Within this paper, a glassy carbon electrode modified with single-walled carbon nanotubes (SWCNTs-GCE) was prepared, and employed for the determination of clorsulon (Clo), which is a frequently used veterinary drug against common liver fluke. The comprehensive topographical and electrochemical characterizations of bare GCE and SWCNTs-GCE were performed by atomic force microscopy, electrochemical impedance spectroscopy, and cyclic voltammetry. Significantly enhanced electrochemical characteristics of SWCNTs-GCE toward a ferrocyanide/ferricyanide redox couple was observed when compared to bare GCE. Further, the prepared sensor was applied for the voltammetric determination of Clo, which was electrochemically investigated for the first time in this work. Voltammetric experiments were performed using square-wave voltammetry with optimized parameters in phosphate buffer solution, pH 6.8, which was selected as the most suitable medium for the determination of Clo. The corresponding current at approx. +1.1 V increased linearly with Clo concentration within two linear dynamic ranges of 0.75-4.00 mu mol L-1 (R-2=0.9934) and 4.00-15.00 mu mol L-1 (R-2=0.9942) with a sensitivity for the first calibration range of 0.76 mu A L mu mol(-1), a limit of detection of 0.19 mu mol L-1, and a limit of quantification of 0.64 mu mol L-1. The developed method was subsequently applied for quantitative analysis of Clo in milk samples with results proving high repeatability and recovery.

Název v anglickém jazyce

A Sensitive Sensor Based on Single-walled Carbon Nanotubes: Its Preparation, Characterization and Application in the Electrochemical Determination of Drug Clorsulon in Milk Samples

Popis výsledku anglicky

Within this paper, a glassy carbon electrode modified with single-walled carbon nanotubes (SWCNTs-GCE) was prepared, and employed for the determination of clorsulon (Clo), which is a frequently used veterinary drug against common liver fluke. The comprehensive topographical and electrochemical characterizations of bare GCE and SWCNTs-GCE were performed by atomic force microscopy, electrochemical impedance spectroscopy, and cyclic voltammetry. Significantly enhanced electrochemical characteristics of SWCNTs-GCE toward a ferrocyanide/ferricyanide redox couple was observed when compared to bare GCE. Further, the prepared sensor was applied for the voltammetric determination of Clo, which was electrochemically investigated for the first time in this work. Voltammetric experiments were performed using square-wave voltammetry with optimized parameters in phosphate buffer solution, pH 6.8, which was selected as the most suitable medium for the determination of Clo. The corresponding current at approx. +1.1 V increased linearly with Clo concentration within two linear dynamic ranges of 0.75-4.00 mu mol L-1 (R-2=0.9934) and 4.00-15.00 mu mol L-1 (R-2=0.9942) with a sensitivity for the first calibration range of 0.76 mu A L mu mol(-1), a limit of detection of 0.19 mu mol L-1, and a limit of quantification of 0.64 mu mol L-1. The developed method was subsequently applied for quantitative analysis of Clo in milk samples with results proving high repeatability and recovery.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Electroanalysis

ISSN

1040-0397

e-ISSN

—

Svazek periodika

32

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

9

Strana od-do

375-383

Kód UT WoS článku

000488015100001

EID výsledku v databázi Scopus

2-s2.0-85074049318