Individual and age-related variation of cellular brain composition in a squamate reptile
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F20%3A10416614" target="_blank" >RIV/00216208:11310/20:10416614 - isvavai.cz</a>
Výsledek na webu
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=kEsrJicewZ" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=kEsrJicewZ</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1098/rsbl.2020.0280" target="_blank" >10.1098/rsbl.2020.0280</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Individual and age-related variation of cellular brain composition in a squamate reptile
Popis výsledku v původním jazyce
Within-species variation in the number of neurons, other brain cells and their allocation to different brain parts is poorly studied. Here, we assess these numbers in a squamate reptile, the Madagascar ground gecko (Paroedura picta). We examined adults from two captive populations and three age groups within one population. Even though reptiles exhibit extensive adult neurogenesis, intrapopulation variation in the number of neurons is similar to that in mice. However, the two populations differed significantly in most measures, highlighting the fact that using only one population can underestimate within-species variation. There is a substantial increase in the number of neurons and decrease in neuronal density in adult geckos relative to hatchlings and an increase in the number of neurons in the telencephalon in fully grown adults relative to sexually mature young adults. This finding implies that adult neurogenesis does not only replace worn out but also adds new telencephalic neurons in reptiles during adulthood. This markedly contrasts with the situation in mammals, where the number of cortical neurons declines with age.
Název v anglickém jazyce
Individual and age-related variation of cellular brain composition in a squamate reptile
Popis výsledku anglicky
Within-species variation in the number of neurons, other brain cells and their allocation to different brain parts is poorly studied. Here, we assess these numbers in a squamate reptile, the Madagascar ground gecko (Paroedura picta). We examined adults from two captive populations and three age groups within one population. Even though reptiles exhibit extensive adult neurogenesis, intrapopulation variation in the number of neurons is similar to that in mice. However, the two populations differed significantly in most measures, highlighting the fact that using only one population can underestimate within-species variation. There is a substantial increase in the number of neurons and decrease in neuronal density in adult geckos relative to hatchlings and an increase in the number of neurons in the telencephalon in fully grown adults relative to sexually mature young adults. This finding implies that adult neurogenesis does not only replace worn out but also adds new telencephalic neurons in reptiles during adulthood. This markedly contrasts with the situation in mammals, where the number of cortical neurons declines with age.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10613 - Zoology
Návaznosti výsledku
Projekt
<a href="/cs/project/GA18-15020S" target="_blank" >GA18-15020S: Evoluce komplexity a procesní kapacity mozku u obojživelníků a plazů: Kvantitativní přístup k porozumění evoluce mozku u čtyřnožců</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2020
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Biology Letters
ISSN
1744-9561
e-ISSN
—
Svazek periodika
16
Číslo periodika v rámci svazku
9
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
6
Strana od-do
20200280
Kód UT WoS článku
000575119300001
EID výsledku v databázi Scopus
2-s2.0-85091594761