Poly(2-oxazoline)-based stimulus-responsive (Co)polymers: An overview of their design, solution properties, surface-chemistries and applications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F20%3A10419864" target="_blank" >RIV/00216208:11310/20:10419864 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=9k0YQj3MUb" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=9k0YQj3MUb</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.progpolymsci.2020.101252" target="_blank" >10.1016/j.progpolymsci.2020.101252</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Poly(2-oxazoline)-based stimulus-responsive (Co)polymers: An overview of their design, solution properties, surface-chemistries and applications

Popis výsledku v původním jazyce

Pseudopeptidic poly(2-oxazoline)s are a special class of bio-inspired polymers with multiple applications, especially in the field of polymer therapeutics. Unsurprisingly, poly(2-oxazoline) has been extensively studied in recent decades, and pioneering studies on these polymers have shown that nonionic, hydrophilic and thermo-responsive poly(2-oxazoline)s are comparable to and sometimes even more advantageous than poly( ethylene glycol) for biomedical applications. Considering their applications in the biomedical field, stimuli-responsive polymer materials open new opportunities for in vivo applications such as on-demand drug delivery, tissue repairing, biosensing and smart coatings, among others. In this context, this article is a comprehensive review of recent advances in stimuli-responsive polymers/interfaces consisting of poly(2-oxazoline)-based &quot;smart&quot; homopolymer and ( co )polymer materials responsive to different single stimulus or to multiple stimuli. In particular, we focus on the synthesis (design strategies), &quot;smart&quot; solution properties (tuning of cloud points), self-assembly (tuning of nanostructures), surface chemistry (surface grafting strategies, antifouling properties, responsive behaviors) and possible biomedical applications of different stimulus-responsive materials based on functionalized poly(2-oxazoline). Accordingly, this review can be used as a benchmark for biopolymer researchers, thereby helping them design innovative functional poly(2-oxazoline)-based &quot;smart&quot; bio-inspired materials for novel applications by highlighting key research gaps and future research avenues in this dynamic and highly relevant field of research.

Název v anglickém jazyce

Poly(2-oxazoline)-based stimulus-responsive (Co)polymers: An overview of their design, solution properties, surface-chemistries and applications

Popis výsledku anglicky

Pseudopeptidic poly(2-oxazoline)s are a special class of bio-inspired polymers with multiple applications, especially in the field of polymer therapeutics. Unsurprisingly, poly(2-oxazoline) has been extensively studied in recent decades, and pioneering studies on these polymers have shown that nonionic, hydrophilic and thermo-responsive poly(2-oxazoline)s are comparable to and sometimes even more advantageous than poly( ethylene glycol) for biomedical applications. Considering their applications in the biomedical field, stimuli-responsive polymer materials open new opportunities for in vivo applications such as on-demand drug delivery, tissue repairing, biosensing and smart coatings, among others. In this context, this article is a comprehensive review of recent advances in stimuli-responsive polymers/interfaces consisting of poly(2-oxazoline)-based &quot;smart&quot; homopolymer and ( co )polymer materials responsive to different single stimulus or to multiple stimuli. In particular, we focus on the synthesis (design strategies), &quot;smart&quot; solution properties (tuning of cloud points), self-assembly (tuning of nanostructures), surface chemistry (surface grafting strategies, antifouling properties, responsive behaviors) and possible biomedical applications of different stimulus-responsive materials based on functionalized poly(2-oxazoline). Accordingly, this review can be used as a benchmark for biopolymer researchers, thereby helping them design innovative functional poly(2-oxazoline)-based &quot;smart&quot; bio-inspired materials for novel applications by highlighting key research gaps and future research avenues in this dynamic and highly relevant field of research.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

<a href="/cs/project/LTAIN19078" target="_blank" >LTAIN19078: Nanostrukturované micely s jedním či více kompartmenty a odezvou na vnější podněty tvořené blokovými kopolymery: Materiály a aplikace</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Progress in Polymer Science

ISSN

0079-6700

e-ISSN

—

Svazek periodika

106

Číslo periodika v rámci svazku

July

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

46

Strana od-do

101252

Kód UT WoS článku

000541865400001

EID výsledku v databázi Scopus

2-s2.0-85085930143