Spectrometric methods in pharmaceutical analysis of glycosaminoglycans: the state-of-the-art

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F20%3A10423516" target="_blank" >RIV/00216208:11310/20:10423516 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=P160QhtxIG" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=P160QhtxIG</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00706-020-02632-3" target="_blank" >10.1007/s00706-020-02632-3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Spectrometric methods in pharmaceutical analysis of glycosaminoglycans: the state-of-the-art

Popis výsledku v původním jazyce

Glycosaminoglycans are important complex carbohydrates that are used in a number of pharmaceutical products. Because glycosaminoglycans are obtained by isolation from biological materials, their pharmaceutical analysis before therapeutic use is of paramount importance. Due to their versatility, wide applicability, non-destructiveness, and in particular the possibility of obtaining a &quot;fingerprint&quot; clearly proving the given chemical specie, spectrometric methods are one of the essential methods used for these analyzes. This review is focused on significant spectrometric methods used in the pharmaceutical analysis of glycosaminoglycans. The advantages and prospects of individual methods (NMR spectrometry, infrared and Raman spectrometry, UV/Vis spectrometry, spectrofluorimetry, chemiluminescence, and circular dichroism) used and methodological aspects of the analysis are discussed. The possibilities of further development and application of spectral methods in the discussed area are outlined. [GRAPHICS] .

Název v anglickém jazyce

Spectrometric methods in pharmaceutical analysis of glycosaminoglycans: the state-of-the-art

Popis výsledku anglicky

Glycosaminoglycans are important complex carbohydrates that are used in a number of pharmaceutical products. Because glycosaminoglycans are obtained by isolation from biological materials, their pharmaceutical analysis before therapeutic use is of paramount importance. Due to their versatility, wide applicability, non-destructiveness, and in particular the possibility of obtaining a &quot;fingerprint&quot; clearly proving the given chemical specie, spectrometric methods are one of the essential methods used for these analyzes. This review is focused on significant spectrometric methods used in the pharmaceutical analysis of glycosaminoglycans. The advantages and prospects of individual methods (NMR spectrometry, infrared and Raman spectrometry, UV/Vis spectrometry, spectrofluorimetry, chemiluminescence, and circular dichroism) used and methodological aspects of the analysis are discussed. The possibilities of further development and application of spectral methods in the discussed area are outlined. [GRAPHICS] .

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Monatshefte für Chemie - Chemical Monthly

ISSN

0026-9247

e-ISSN

—

Svazek periodika

151

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

AT - Rakouská republika

Počet stran výsledku

8

Strana od-do

1185-1192

Kód UT WoS článku

000537345300001

EID výsledku v databázi Scopus

2-s2.0-85085870813