Gaining Insight into Large Gene Families with the Aid of Bioinformatic Tools

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F23%3A10478613" target="_blank" >RIV/00216208:11310/23:10478613 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1007/978-1-0716-2867-6_13" target="_blank" >https://doi.org/10.1007/978-1-0716-2867-6_13</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-1-0716-2867-6_13" target="_blank" >10.1007/978-1-0716-2867-6_13</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Gaining Insight into Large Gene Families with the Aid of Bioinformatic Tools

Popis výsledku v původním jazyce

Proteins participating in plant cell morphogenesis are often encoded by large gene families, in some cases comprising paralogs with variable (modular) domain organization, as in the case of the formin (FH2 protein) family of actin nucleators that can have also additional functions. Unravelling the phylogeny of such a complex gene family brings a number of specific challenges but may be crucial for predictions of protein function and for experimental design. Here we present an overview of our &quot;cottage industry&quot; semi-manual bioinformatic approach, based mostly, though not exclusively, on freely available software tools, which we used to obtain insight into the evolutionary history of plant FH2 proteins and some other components of the plant cell morphogenesis apparatus.

Název v anglickém jazyce

Gaining Insight into Large Gene Families with the Aid of Bioinformatic Tools

Popis výsledku anglicky

Proteins participating in plant cell morphogenesis are often encoded by large gene families, in some cases comprising paralogs with variable (modular) domain organization, as in the case of the formin (FH2 protein) family of actin nucleators that can have also additional functions. Unravelling the phylogeny of such a complex gene family brings a number of specific challenges but may be crucial for predictions of protein function and for experimental design. Here we present an overview of our &quot;cottage industry&quot; semi-manual bioinformatic approach, based mostly, though not exclusively, on freely available software tools, which we used to obtain insight into the evolutionary history of plant FH2 proteins and some other components of the plant cell morphogenesis apparatus.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

10600 - Biological sciences

Projekt

<a href="/cs/project/GA22-33471S" target="_blank" >GA22-33471S: Forminy třídy I v propojení dynamiky membrán a cytoskeletu při vývoji kořene</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

The Plant Cytoskeleton

ISBN

978-1-07-162866-9

Počet stran výsledku

19

Strana od-do

173-191

Počet stran knihy

369

Název nakladatele

Humana New York, NY

Místo vydání

New York

Kód UT WoS kapitoly

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