Are contributory causes of death in part 2 of the death certificate mediators of chains of morbid events leading to death?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F25%3A10502169" target="_blank" >RIV/00216208:11310/25:10502169 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=KWo2-42GDx" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=KWo2-42GDx</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s12963-025-00394-w" target="_blank" >10.1186/s12963-025-00394-w</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Are contributory causes of death in part 2 of the death certificate mediators of chains of morbid events leading to death?

Popis výsledku v původním jazyce

Background: In the United States, over half of all deaths are attributed to five leading underlying causes of death (at the ICD-3 digit level). However, these underlying causes represent only 25% of the total medical information documented on death certificates. While previous studies have investigated associations between causes of death, none have specifically examined the mechanisms of interaction among these causes. This study aims to explore the role of contributory causes of death recorded in Part 2 of the death certificate in the lethal process.Methods: Working with U.S. Multiple Cause of Death Microdata in 2019, we use causal pie models to model the synergy between multiple causes of death.Results: The findings show how contributory causes in Part 2 affect the sequence of morbid events leading to death. Three broad categories of roles can be distinguished: (i) some contributory causes act as mediators in the chain of morbid events, (ii) others do not exhibit any interaction with the conditions listed in Part 1, and (iii) some might play a role in the development of underlying causes.Conclusion: Contributory causes listed in Part 2 play a crucial role in transitions to terminal morbid states. There is evidence that these are more than just conditions without a direct relationship to the underlying cause of death.

Název v anglickém jazyce

Are contributory causes of death in part 2 of the death certificate mediators of chains of morbid events leading to death?

Popis výsledku anglicky

Background: In the United States, over half of all deaths are attributed to five leading underlying causes of death (at the ICD-3 digit level). However, these underlying causes represent only 25% of the total medical information documented on death certificates. While previous studies have investigated associations between causes of death, none have specifically examined the mechanisms of interaction among these causes. This study aims to explore the role of contributory causes of death recorded in Part 2 of the death certificate in the lethal process.Methods: Working with U.S. Multiple Cause of Death Microdata in 2019, we use causal pie models to model the synergy between multiple causes of death.Results: The findings show how contributory causes in Part 2 affect the sequence of morbid events leading to death. Three broad categories of roles can be distinguished: (i) some contributory causes act as mediators in the chain of morbid events, (ii) others do not exhibit any interaction with the conditions listed in Part 1, and (iii) some might play a role in the development of underlying causes.Conclusion: Contributory causes listed in Part 2 play a crucial role in transitions to terminal morbid states. There is evidence that these are more than just conditions without a direct relationship to the underlying cause of death.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

50402 - Demography

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Population Health Metrics

ISSN

1478-7954

e-ISSN

1478-7954

Svazek periodika

23

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

13

Strana od-do

46

Kód UT WoS článku

001545589900001

EID výsledku v databázi Scopus

2-s2.0-105012863243