Parallel fluorescence and phosphorescence monitoring of singlet oxygen photosensitization in rats
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F15%3A10314725" target="_blank" >RIV/00216208:11320/15:10314725 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216208:11120/15:43910375
Výsledek na webu
<a href="http://dx.doi.org/10.1142/S1793545815500376" target="_blank" >http://dx.doi.org/10.1142/S1793545815500376</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1142/S1793545815500376" target="_blank" >10.1142/S1793545815500376</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Parallel fluorescence and phosphorescence monitoring of singlet oxygen photosensitization in rats
Popis výsledku v původním jazyce
'The time- and spectral-resolved set-up for measurements of weak infrared luminescence of photosensitizers (PSs) and singlet oxygen using optical lightguides was used on skin of laboratory animals in vivo. Wistar rats with abdominal incisions treated bymethylis aminolevulinitis (MAL) were used as a model. A control group of animals with abdominal incisions was also tested. Spectrally resolved fluorescence of the PS was acquired during the treatment from the same spot. The intensity and spectral profileof the fluorescence signal from the skin can be used to guide the detection setup to the investigated spots in the lesion. The rate of bleaching of Protoporphyrin IX band and appearance of a band of its photoproducts during the treatment can be characterized by the exposition E-D, under which the latter becomes dominant feature in fluorescence spectrum. E-D value differs statistically significantly between the normal skin and the lesion treated by MAL. No direct proportionality was foun
Název v anglickém jazyce
Parallel fluorescence and phosphorescence monitoring of singlet oxygen photosensitization in rats
Popis výsledku anglicky
'The time- and spectral-resolved set-up for measurements of weak infrared luminescence of photosensitizers (PSs) and singlet oxygen using optical lightguides was used on skin of laboratory animals in vivo. Wistar rats with abdominal incisions treated bymethylis aminolevulinitis (MAL) were used as a model. A control group of animals with abdominal incisions was also tested. Spectrally resolved fluorescence of the PS was acquired during the treatment from the same spot. The intensity and spectral profileof the fluorescence signal from the skin can be used to guide the detection setup to the investigated spots in the lesion. The rate of bleaching of Protoporphyrin IX band and appearance of a band of its photoproducts during the treatment can be characterized by the exposition E-D, under which the latter becomes dominant feature in fluorescence spectrum. E-D value differs statistically significantly between the normal skin and the lesion treated by MAL. No direct proportionality was foun
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
BO - Biofyzika
OECD FORD obor
—
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Journal of Innovative Optical Health Sciences
ISSN
1793-5458
e-ISSN
—
Svazek periodika
8
Číslo periodika v rámci svazku
6
Stát vydavatele periodika
SG - Singapurská republika
Počet stran výsledku
14
Strana od-do
—
Kód UT WoS článku
000363734000007
EID výsledku v databázi Scopus
2-s2.0-84946471407