Relations between behavioral risk factors and genomic constitution in essential hypertension

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F00%3A00002862" target="_blank" >RIV/00216224:14110/00:00002862 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Relations between behavioral risk factors and genomic constitution in essential hypertension

Popis výsledku v původním jazyce

The aim of the study was to associate alleles and/or genotype of the candidate gene polymorphisms for essential hypertension with some known cardiovascular risk factors as blood pressure parameters, smoking, alcohol consumption, obesity, type A behavioral pattern score and emotional load in 202 hypertensives and 196 normotensives subjects. No significant association among the gene polymorphisms and normotensives-hypertensives, blood pressure parameters from ambulatory blood pressure monitoring, smoking,salt consumption, alcohol consumption, BMI were found when single gene differences were calculated. When genotype concurrence of the two polymorphisms was evaluated, marginal association with TABP score was found(P=0.030). Three genotypes (IITT,IDMT, DDMM) were found more frequently in subjects with higher emotional load compared to the other genotype combinations (P=0.064).

Název v anglickém jazyce

Relations between behavioral risk factors and genomic constitution in essential hypertension

Popis výsledku anglicky

The aim of the study was to associate alleles and/or genotype of the candidate gene polymorphisms for essential hypertension with some known cardiovascular risk factors as blood pressure parameters, smoking, alcohol consumption, obesity, type A behavioral pattern score and emotional load in 202 hypertensives and 196 normotensives subjects. No significant association among the gene polymorphisms and normotensives-hypertensives, blood pressure parameters from ambulatory blood pressure monitoring, smoking,salt consumption, alcohol consumption, BMI were found when single gene differences were calculated. When genotype concurrence of the two polymorphisms was evaluated, marginal association with TABP score was found(P=0.030). Three genotypes (IITT,IDMT, DDMM) were found more frequently in subjects with higher emotional load compared to the other genotype combinations (P=0.064).

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2000

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Homeostasis

ISSN

1960-7560

e-ISSN

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Svazek periodika

40

Číslo periodika v rámci svazku

3-4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

3

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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