IMMUNOHISTOCHEMICAL DIFFERENCES IN THE ECM CONTENT ALONGSIDE AFFERENT AND MOTOR AXONS IN RELATION TO THE POSITION OF THE DORSAL ROOT GANGLION

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F00%3A00003131" target="_blank" >RIV/00216224:14110/00:00003131 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

IMMUNOHISTOCHEMICAL DIFFERENCES IN THE ECM CONTENT ALONGSIDE AFFERENT AND MOTOR AXONS IN RELATION TO THE POSITION OF THE DORSAL ROOT GANGLION

Popis výsledku v původním jazyce

To reveal different microenvironmental conditions for motor and afferent axons we have analyzed immunohistochemically some ECM components and adhesion molecules (laminin-2, -3, fibronectin, thrombospondin, tenascin, chondroitin sulfate, and HNK-1) in thespinal roots and branches of the spinal nerve.Our results revealed no differences in the fibronectin immunofluorescence between dorsal and ventral roots as well as dorsal and ventral branches of the spinal nerve. There were also no differences between ventral and dorsal branches in the thrombospondin occurrence peripheral to DRG, and no differences were found between ventral and dorsal root contents of both laminin-2 and -3 central to the DRG. A higher immunofluorescence staining for HNK-1 and CS-56 was proved in the dorsal root as well as dorsal branch of the spinal nerve in contrast to the ventral root and branch. The greater amount of thrombospondin and tenascin molecules was disclosed in the dorsal roots than ventral ones, while hi

Název v anglickém jazyce

IMMUNOHISTOCHEMICAL DIFFERENCES IN THE ECM CONTENT ALONGSIDE AFFERENT AND MOTOR AXONS IN RELATION TO THE POSITION OF THE DORSAL ROOT GANGLION

Popis výsledku anglicky

To reveal different microenvironmental conditions for motor and afferent axons we have analyzed immunohistochemically some ECM components and adhesion molecules (laminin-2, -3, fibronectin, thrombospondin, tenascin, chondroitin sulfate, and HNK-1) in thespinal roots and branches of the spinal nerve.Our results revealed no differences in the fibronectin immunofluorescence between dorsal and ventral roots as well as dorsal and ventral branches of the spinal nerve. There were also no differences between ventral and dorsal branches in the thrombospondin occurrence peripheral to DRG, and no differences were found between ventral and dorsal root contents of both laminin-2 and -3 central to the DRG. A higher immunofluorescence staining for HNK-1 and CS-56 was proved in the dorsal root as well as dorsal branch of the spinal nerve in contrast to the ventral root and branch. The greater amount of thrombospondin and tenascin molecules was disclosed in the dorsal roots than ventral ones, while hi

Druh

D - Stať ve sborníku

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/GA309%2F00%2F0407" target="_blank" >GA309/00/0407: Celulární a extracelulární prostředí pro regeneraci axonů při kořenových a distálních lezích periferních nervů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2000

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

37th Proceedings of Czech Society of Histochemistry and Cytochemistry

ISBN

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ISSN

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e-ISSN

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Počet stran výsledku

1

Strana od-do

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Název nakladatele

MU Brno

Místo vydání

Brno

Místo konání akce

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Datum konání akce

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Typ akce podle státní příslušnosti

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Kód UT WoS článku

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