LIGNANS OF SCHISANDRA CHINENSIS: ANALYSIS IN PLANT CELL CULTURE AND ANTIPROLIFERATIVE ACTIVITY

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F03%3A00008061" target="_blank" >RIV/00216224:14110/03:00008061 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

LIGNANS OF SCHISANDRA CHINENSIS: ANALYSIS IN PLANT CELL CULTURE AND ANTIPROLIFERATIVE ACTIVITY

Popis výsledku v původním jazyce

Dibenzocyclo[a,c]diene lignans occur exclusively in genera Schisandra and Kadsura (Schisandraceae/Magnoliaceae). Schisnadra chinensis is well-known medicinal plants of traditional Chinese medicine in which fruits have been used as tonic and antitusic. These lignans have been shown to possess a broad range of biological effects, including antivirral, antioxidative and hepatoprotective activities. Content of lignans in fruits of the plants is relatively low (~1 %) and is composed of at least thirty lignans. Moreover, contents of individual lignans considerably vary from plant to plant. Plant cell culture may represent a solution of the supply of these lignans. We determined the production of lignans in cell culture of S. chinensis using HPLC. Our preliminary results showed, that amount of lignans in plant cell cultures was lower than that in fruits and leaves. The main lignan in samples of cell cultures was deoxyschizandrin, its maximum yield reached 0.13 % based on biomass dry weight. T

Název v anglickém jazyce

LIGNANS OF SCHISANDRA CHINENSIS: ANALYSIS IN PLANT CELL CULTURE AND ANTIPROLIFERATIVE ACTIVITY

Popis výsledku anglicky

Dibenzocyclo[a,c]diene lignans occur exclusively in genera Schisandra and Kadsura (Schisandraceae/Magnoliaceae). Schisnadra chinensis is well-known medicinal plants of traditional Chinese medicine in which fruits have been used as tonic and antitusic. These lignans have been shown to possess a broad range of biological effects, including antivirral, antioxidative and hepatoprotective activities. Content of lignans in fruits of the plants is relatively low (~1 %) and is composed of at least thirty lignans. Moreover, contents of individual lignans considerably vary from plant to plant. Plant cell culture may represent a solution of the supply of these lignans. We determined the production of lignans in cell culture of S. chinensis using HPLC. Our preliminary results showed, that amount of lignans in plant cell cultures was lower than that in fruits and leaves. The main lignan in samples of cell cultures was deoxyschizandrin, its maximum yield reached 0.13 % based on biomass dry weight. T

Druh

B - Odborná kniha

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

<a href="/cs/project/GA521%2F02%2F1129" target="_blank" >GA521/02/1129: Využití biotechnologických metod k produkci sekundárních metabolitů, šlechtění a mikropropagaci léčivé rostliny klanoprašky čínské</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2003

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

ISBN

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Počet stran knihy

1

Název nakladatele

The Phytochemical Society of Europe

Místo vydání

Dusseldorf

Kód UT WoS knihy

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