END-TO-SIDE ANASTOMOSIS OF PERIPHERAL NERVE IN CLINICAL AND EXPERIMENTAL MODEL

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F03%3A00009623" target="_blank" >RIV/00216224:14110/03:00009623 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

END-TO-SIDE ANASTOMOSIS OF PERIPHERAL NERVE IN CLINICAL AND EXPERIMENTAL MODEL

Popis výsledku v původním jazyce

The results of 13 patients with end-to-side (ETS) anastomosis of the axillary nerve to various donor nerves were evaluated by means of functional and electrophysiological methods following avulsion and subsequent reconstruction of the brachial plexus. ETS anastomosis of the rat musculocutaneus nerve (n=12) with the ulnar one was used in the experimental model. Fair and good results were achieved in neurotization of the axillary nerve in 75% of patients with follow up longer than 24 months. Electrophysiology proved reinnervation in 100% of the patients. The average muscle strength, according to the muscle test, was 3.80. Retrograde staining in the experimental model demonstrated the reinnervation of the rat biceps muscles 3 months from ETS anastomosis,mainly by collateral reinnervation from the ulnar nerve. The ulnar nerve motoneurons (70ą13) were able to send off collateral sprouts from their intact axons into the musculocutaneus nerve. Other motoneurons of the same pool (21ą4) regene

Název v anglickém jazyce

END-TO-SIDE ANASTOMOSIS OF PERIPHERAL NERVE IN CLINICAL AND EXPERIMENTAL MODEL

Popis výsledku anglicky

The results of 13 patients with end-to-side (ETS) anastomosis of the axillary nerve to various donor nerves were evaluated by means of functional and electrophysiological methods following avulsion and subsequent reconstruction of the brachial plexus. ETS anastomosis of the rat musculocutaneus nerve (n=12) with the ulnar one was used in the experimental model. Fair and good results were achieved in neurotization of the axillary nerve in 75% of patients with follow up longer than 24 months. Electrophysiology proved reinnervation in 100% of the patients. The average muscle strength, according to the muscle test, was 3.80. Retrograde staining in the experimental model demonstrated the reinnervation of the rat biceps muscles 3 months from ETS anastomosis,mainly by collateral reinnervation from the ulnar nerve. The ulnar nerve motoneurons (70ą13) were able to send off collateral sprouts from their intact axons into the musculocutaneus nerve. Other motoneurons of the same pool (21ą4) regene

Druh

C - Kapitola v odborné knize

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2003

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Developments in Neuroscience

ISBN

0-444-51488-0

Počet stran výsledku

7

Strana od-do

231

Počet stran knihy

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Název nakladatele

Elsevier

Místo vydání

Nizozemí

Kód UT WoS kapitoly

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