Srovnání poměru trough/peak betaxolol hydrochloridu a metoprololu u pacientů s čerstvě zjištěnou hypertenzí

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F04%3A00010156" target="_blank" >RIV/00216224:14110/04:00010156 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Comparison Evaluation of Trough/Peak Ratio Betaxolol Hydrochloride and Metoprolole in Patients with Newly Diagnosed Hypertension.

Popis výsledku v původním jazyce

One of the important characteristic features of the new antihypertensive drugs is its 24-hour effectiveness. If the drug reaches the mean trough/peak over 50% it can be dosed once daily. Betablockers are one of initial drug choice in young patients withhypertension. We evaluated 60 patients in two groups before and after the 3months of treatment with 20mg betaxolol hydrochloride once daily or 200mg metoprolole once daily. For the peak value we used the mean BP from the 3rd - 6th hour after the using ofbetaxolol hydrochloride or metoprolole, for the trough value the mean BP from the 22nd to 24th hour of the measurement was used, 30 minutes after getting up in the morning and excluding the influence of the hospital surroundings. Results: Trough/peak ratio betaxolol hydrochloride is 78% by the systolic BP, and it is 77% by the diastolic BP. Trough/peak ratio metoprolole is 75% by the systolic BP, and it is 71% by the diastolic BP. Conclusion: Both drugs, betaxolol hydrochloride and meto

Název v anglickém jazyce

Comparison Evaluation of Trough/Peak Ratio Betaxolol Hydrochloride and Metoprolole in Patients with Newly Diagnosed Hypertension.

Popis výsledku anglicky

One of the important characteristic features of the new antihypertensive drugs is its 24-hour effectiveness. If the drug reaches the mean trough/peak over 50% it can be dosed once daily. Betablockers are one of initial drug choice in young patients withhypertension. We evaluated 60 patients in two groups before and after the 3months of treatment with 20mg betaxolol hydrochloride once daily or 200mg metoprolole once daily. For the peak value we used the mean BP from the 3rd - 6th hour after the using ofbetaxolol hydrochloride or metoprolole, for the trough value the mean BP from the 22nd to 24th hour of the measurement was used, 30 minutes after getting up in the morning and excluding the influence of the hospital surroundings. Results: Trough/peak ratio betaxolol hydrochloride is 78% by the systolic BP, and it is 77% by the diastolic BP. Trough/peak ratio metoprolole is 75% by the systolic BP, and it is 71% by the diastolic BP. Conclusion: Both drugs, betaxolol hydrochloride and meto

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Hypertension

ISSN

09521178

e-ISSN

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Svazek periodika

2004/22

Číslo periodika v rámci svazku

Suppl 2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

1

Strana od-do

"S259"

Kód UT WoS článku

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EID výsledku v databázi Scopus

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