Comparing genomes of pathogenic and non-pathogenic spirochetes: DNA-microarray hybridizations, whole genome fingerprinting and DNA sequencing.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F05%3A00013211" target="_blank" >RIV/00216224:14110/05:00013211 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Comparing genomes of pathogenic and non-pathogenic spirochetes: DNA-microarray hybridizations, whole genome fingerprinting and DNA sequencing.

Popis výsledku v původním jazyce

Genomes of closely related treponemes, Treponema pallidum ssp. pallidum (strains Nichols and SS14) and Treponema pallidum ssp. pertenue (Samoan D) were compared with the genome of Treponema paraluiscuniculi (strain Cuniculi A) using comparative genomic techniques. T. pallidum ssp. pallidum is the causative agent of highly invasive human disease syphilis, T. pallidum ssp. pertenue is the causative agent of yaws and T. paraluiscuniculi is not pathogenic to humans. When compared to Nichols genome, 1, 8 and34 differences in the BamH I target restriction sites and 3, 7 and 20 indels were found in the genome of SS14, Samoan D and T. paraluiscuniculi, respectively.

Název v anglickém jazyce

Comparing genomes of pathogenic and non-pathogenic spirochetes: DNA-microarray hybridizations, whole genome fingerprinting and DNA sequencing.

Popis výsledku anglicky

Genomes of closely related treponemes, Treponema pallidum ssp. pallidum (strains Nichols and SS14) and Treponema pallidum ssp. pertenue (Samoan D) were compared with the genome of Treponema paraluiscuniculi (strain Cuniculi A) using comparative genomic techniques. T. pallidum ssp. pallidum is the causative agent of highly invasive human disease syphilis, T. pallidum ssp. pertenue is the causative agent of yaws and T. paraluiscuniculi is not pathogenic to humans. When compared to Nichols genome, 1, 8 and34 differences in the BamH I target restriction sites and 3, 7 and 20 indels were found in the genome of SS14, Samoan D and T. paraluiscuniculi, respectively.

Druh

O - Ostatní výsledky

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů