EFFECT OF ANTHRACYCLINE THERAPY ON CARDIOVASCULAR REGULATION AND PHYSICAL ACTIVITY
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F06%3A00016959" target="_blank" >RIV/00216224:14110/06:00016959 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
EFFECT OF ANTHRACYCLINE THERAPY ON CARDIOVASCULAR REGULATION AND PHYSICAL ACTIVITY
Popis výsledku v původním jazyce
We followed effect of anthracycline therapy on physical activity, body and cardiovascular parameters in children treated for malignant tumor. We examined 21 subjects after antitumor therapy (M; 15.5b3.2 years) and 32 healthy subjects (Co; 15.7b2.1 years). In group M, 8 subjects had a non-cardiotoxic therapy (A0), and 13 children were treated with anthracyclines (A+). In group A+ vs. A0 and Co, we found significantly lower SBP. A+ compared with Co had higher BRSf; lower weight and height; lower total physical activity and physical activity related to 1 kg of body weight. In whole group M, we found negative correlation between dose of anthracyclines and SBP and total physical activity. The multiple regression in group M shown that SBP was significantly related to the duration of period without antitumor therapy and to the dosage of anthracyclines. BRSf significantly correlated with body weight, physical activity related to 1 kg of body weight, time since therapy and SBP.
Název v anglickém jazyce
EFFECT OF ANTHRACYCLINE THERAPY ON CARDIOVASCULAR REGULATION AND PHYSICAL ACTIVITY
Popis výsledku anglicky
We followed effect of anthracycline therapy on physical activity, body and cardiovascular parameters in children treated for malignant tumor. We examined 21 subjects after antitumor therapy (M; 15.5b3.2 years) and 32 healthy subjects (Co; 15.7b2.1 years). In group M, 8 subjects had a non-cardiotoxic therapy (A0), and 13 children were treated with anthracyclines (A+). In group A+ vs. A0 and Co, we found significantly lower SBP. A+ compared with Co had higher BRSf; lower weight and height; lower total physical activity and physical activity related to 1 kg of body weight. In whole group M, we found negative correlation between dose of anthracyclines and SBP and total physical activity. The multiple regression in group M shown that SBP was significantly related to the duration of period without antitumor therapy and to the dosage of anthracyclines. BRSf significantly correlated with body weight, physical activity related to 1 kg of body weight, time since therapy and SBP.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
ED - Fyziologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/NR8006" target="_blank" >NR8006: Autonomní oběhové funkce, funkce myokardu a kardiorespirační funkce u dětí a adolescentů po léčbě zhoubného nádoru</a><br>
Návaznosti
Z - Vyzkumny zamer (s odkazem do CEZ)
Ostatní
Rok uplatnění
2006
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů