Léčba negativních příznaků schizofrenie pomocí repetitivní transkraniální magnetické stimulace v podmínkách dvojitě zaslepené studie

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F07%3A00019092" target="_blank" >RIV/00216224:14110/07:00019092 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Treatment of negative symptoms of schizophrenia using repetitive transcranial magnetic stimulation in a double-blind, randomized controlled study

Popis výsledku v původním jazyce

Twenty two schizophrenic patients on stable antipsychotic medication with prominent negative symptoms were included into the trial. They were divided into two groups: eleven of them were treated with effective rTMS and eleven with ineffective sham rTMS.The inefficacy of sham rTMS was achieved through stimulation coil position. Stimulation was applied to the left dorsolateral prefrontal cortex. Stimulation frequency was 10Hz. Stimulation intensity was 110% of the motor threshold intensity. Each patientreceived 15 rTMS sessions on 15 consecutive working days. Each daily session consisted of 15 trains of 10 seconds duration and 30 seconds intertrains intervals. It means 1500 stimuli per session. During real rTMS treatment the statistical significant decrease of negative symptoms was found (about 29% in negative subscale PANSS and 50% in SANS). No adverse events occured during therapy except of mild headache. In sham rTMS treatment the decrease of negative symptoms was found too, but was

Název v anglickém jazyce

Treatment of negative symptoms of schizophrenia using repetitive transcranial magnetic stimulation in a double-blind, randomized controlled study

Popis výsledku anglicky

Twenty two schizophrenic patients on stable antipsychotic medication with prominent negative symptoms were included into the trial. They were divided into two groups: eleven of them were treated with effective rTMS and eleven with ineffective sham rTMS.The inefficacy of sham rTMS was achieved through stimulation coil position. Stimulation was applied to the left dorsolateral prefrontal cortex. Stimulation frequency was 10Hz. Stimulation intensity was 110% of the motor threshold intensity. Each patientreceived 15 rTMS sessions on 15 consecutive working days. Each daily session consisted of 15 trains of 10 seconds duration and 30 seconds intertrains intervals. It means 1500 stimuli per session. During real rTMS treatment the statistical significant decrease of negative symptoms was found (about 29% in negative subscale PANSS and 50% in SANS). No adverse events occured during therapy except of mild headache. In sham rTMS treatment the decrease of negative symptoms was found too, but was

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FL - Psychiatrie, sexuologie

OECD FORD obor

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Projekt

<a href="/cs/project/NR7986" target="_blank" >NR7986: Ovlivnění negativních příznaků schizofrenie pomocí repetitivní transkraniální magnetické stimulace (rTMS) v podmínkách jednoduše slepé, randomizované studie.</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Schizophrenia Research

ISSN

0920-9964

e-ISSN

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Svazek periodika

95

Číslo periodika v rámci svazku

95

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

151-157

Kód UT WoS článku

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EID výsledku v databázi Scopus

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