No association of defined variability in leptin, leptin receptor, adiponectin, proopiomelanocortin and ghrelin gene with food preferences in the Czech population

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F08%3A00033307" target="_blank" >RIV/00216224:14110/08:00033307 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

No association of defined variability in leptin, leptin receptor, adiponectin, proopiomelanocortin and ghrelin gene with food preferences in the Czech population

Popis výsledku v původním jazyce

Background: Previously, it has been reported that mutations in the genes encoding for adipokines may be associated with impaired food intake and may serve as potential obesity biomarkers. Aims: The aim of this study was to investigate the possible associations of defined variability in leptin, leptin receptor, adiponectin, proopiomelanocortin and ghrelin genes with food preferences in obese and non-obese Czech population and evaluate their potential as the obesity susceptibility genes. Material and methods: Using PCR with following restriction analysis, we studied here 185 volunteers. Basic anthropometrical characteristics associated to obesity were measured and the food intake was monitored using 7 day record method. In the group of obese individual,a subset of 34 morbidly obese patients was set off that were available for plasma leptin and soluble leptin receptor levels measurement.

Název v anglickém jazyce

No association of defined variability in leptin, leptin receptor, adiponectin, proopiomelanocortin and ghrelin gene with food preferences in the Czech population

Popis výsledku anglicky

Background: Previously, it has been reported that mutations in the genes encoding for adipokines may be associated with impaired food intake and may serve as potential obesity biomarkers. Aims: The aim of this study was to investigate the possible associations of defined variability in leptin, leptin receptor, adiponectin, proopiomelanocortin and ghrelin genes with food preferences in obese and non-obese Czech population and evaluate their potential as the obesity susceptibility genes. Material and methods: Using PCR with following restriction analysis, we studied here 185 volunteers. Basic anthropometrical characteristics associated to obesity were measured and the food intake was monitored using 7 day record method. In the group of obese individual,a subset of 34 morbidly obese patients was set off that were available for plasma leptin and soluble leptin receptor levels measurement.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Nutritional Neuroscience

ISSN

1028-415X

e-ISSN

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Svazek periodika

2008

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

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Kód UT WoS článku

000256999200001

EID výsledku v databázi Scopus

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