Regression of histopathological myopathic changes in patients with critical illness neuromuscular disorders

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F09%3A00038026" target="_blank" >RIV/00216224:14110/09:00038026 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00179906:_____/09:00201530

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Regression of histopathological myopathic changes in patients with critical illness neuromuscular disorders

Popis výsledku v původním jazyce

Histopathological analysis of 52 muscle biopsies from 43 adult critically ill patients was performed to determine the differential diagnosis and course of neuromuscular involvement in critically ill patients suffering from critical illness polyneuropathyor myopathy. The first histopathological examination in all 43 patients revealed signs of neuropathy in 2 biopsies, myopathy in 19 biopsies, and neuromyopathy in 18, including type 2 fibre atrophy. A repeat study of 9 patients showed that the histopathological features changed in all cases. A second biopsy performed several months or years after the first revealed that myopathic features had regressed and either recovery to normal histopathological findings had occurred or evidence of a persistent neurogenic lesion was found. The results indicate that muscle involvement in critically ill patients is reversible.

Název v anglickém jazyce

Regression of histopathological myopathic changes in patients with critical illness neuromuscular disorders

Popis výsledku anglicky

Histopathological analysis of 52 muscle biopsies from 43 adult critically ill patients was performed to determine the differential diagnosis and course of neuromuscular involvement in critically ill patients suffering from critical illness polyneuropathyor myopathy. The first histopathological examination in all 43 patients revealed signs of neuropathy in 2 biopsies, myopathy in 19 biopsies, and neuromyopathy in 18, including type 2 fibre atrophy. A repeat study of 9 patients showed that the histopathological features changed in all cases. A second biopsy performed several months or years after the first revealed that myopathic features had regressed and either recovery to normal histopathological findings had occurred or evidence of a persistent neurogenic lesion was found. The results indicate that muscle involvement in critically ill patients is reversible.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Scripta Medica

ISSN

1211-3395

e-ISSN

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Svazek periodika

82

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

11

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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