Etiology of small-fiber neuropathy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F09%3A00038063" target="_blank" >RIV/00216224:14110/09:00038063 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/65269705:_____/09:#0000743

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Etiology of small-fiber neuropathy

Popis výsledku v původním jazyce

The aim was to evaluate the etiology in a group of 84 patients with painful sensory neuropathy with predominant small-fiber dysfunction(54 men,30 women,median:58; range:25-83 years).Involvement of small nerve fibers was verified by abnormal thermal thresholds and/or reduced intraepidermal nerve fiber densities.Motor signs or symptoms or significant clinical signs of sensory large-fiber involvement were exclusionary;33 patients,however,had sensory nerve conduction abnormalities.The multivariate regression model disclosed that diabetes mellitus(odds ratio [OR]=4.08),chronic alcoholism(OR=5.31),and serum cholesterol levels(OR=4.51)were the only parameters independently associated with small-fiber involvement.No possible etiology was detected in 19 patients(22.6%).In conclusion,the spectrum of risk factors and proportion of idiopathic cases in geographically defined small-fiber polyneuropathy sample is similar to that referred in large-fiber polyneuropathy.

Název v anglickém jazyce

Etiology of small-fiber neuropathy

Popis výsledku anglicky

The aim was to evaluate the etiology in a group of 84 patients with painful sensory neuropathy with predominant small-fiber dysfunction(54 men,30 women,median:58; range:25-83 years).Involvement of small nerve fibers was verified by abnormal thermal thresholds and/or reduced intraepidermal nerve fiber densities.Motor signs or symptoms or significant clinical signs of sensory large-fiber involvement were exclusionary;33 patients,however,had sensory nerve conduction abnormalities.The multivariate regression model disclosed that diabetes mellitus(odds ratio [OR]=4.08),chronic alcoholism(OR=5.31),and serum cholesterol levels(OR=4.51)were the only parameters independently associated with small-fiber involvement.No possible etiology was detected in 19 patients(22.6%).In conclusion,the spectrum of risk factors and proportion of idiopathic cases in geographically defined small-fiber polyneuropathy sample is similar to that referred in large-fiber polyneuropathy.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/NS9667" target="_blank" >NS9667: Bolestivá diabetická neuropatie</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of the Peripheral Nervous System

ISSN

1085-9489

e-ISSN

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Svazek periodika

14

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

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Kód UT WoS článku

000271639200004

EID výsledku v databázi Scopus

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